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Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART.
Banga R, Procopio FA, Lana E, Gladkov GT, Roseto I, Parsons EM, Lian X, Armani-Tourret M, Bellefroid M, Gao C, Kauzlaric A, Foglierini M, Alfageme-Abello O, Sluka SHM, Munoz O, Mastrangelo A, Fenwick C, Muller Y, Mkindi CG, Daubenberger C, Cavassini M, Trunfio R, Déglise S, Corpataux JM, Delorenzi M, Lichterfeld M, Pantaleo G, Perreau M. Banga R, et al. Among authors: lian x. Cell Host Microbe. 2023 Oct 11;31(10):1714-1731.e9. doi: 10.1016/j.chom.2023.08.020. Epub 2023 Sep 25. Cell Host Microbe. 2023. PMID: 37751747 Free PMC article.
Distinct viral reservoirs in individuals with spontaneous control of HIV-1.
Jiang C, Lian X, Gao C, Sun X, Einkauf KB, Chevalier JM, Chen SMY, Hua S, Rhee B, Chang K, Blackmer JE, Osborn M, Peluso MJ, Hoh R, Somsouk M, Milush J, Bertagnolli LN, Sweet SE, Varriale JA, Burbelo PD, Chun TW, Laird GM, Serrao E, Engelman AN, Carrington M, Siliciano RF, Siliciano JM, Deeks SG, Walker BD, Lichterfeld M, Yu XG. Jiang C, et al. Among authors: lian x. Nature. 2020 Sep;585(7824):261-267. doi: 10.1038/s41586-020-2651-8. Epub 2020 Aug 26. Nature. 2020. PMID: 32848246 Free PMC article.
Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia.
Collins DR, Urbach JM, Racenet ZJ, Arshad U, Power KA, Newman RM, Mylvaganam GH, Ly NL, Lian X, Rull A, Rassadkina Y, Yanez AG, Peluso MJ, Deeks SG, Vidal F, Lichterfeld M, Yu XG, Gaiha GD, Allen TM, Walker BD. Collins DR, et al. Among authors: lian x. Immunity. 2021 Oct 12;54(10):2372-2384.e7. doi: 10.1016/j.immuni.2021.08.007. Epub 2021 Sep 7. Immunity. 2021. PMID: 34496223 Free PMC article.
A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation.
Turk G, Seiger K, Lian X, Sun W, Parsons EM, Gao C, Rassadkina Y, Polo ML, Czernikier A, Ghiglione Y, Vellicce A, Varriale J, Lai J, Yuki Y, Martin M, Rhodes A, Lewin SR, Walker BD, Carrington M, Siliciano R, Siliciano J, Lichterfeld M, Laufer N, Yu XG. Turk G, et al. Among authors: lian x. Ann Intern Med. 2022 Jan;175(1):95-100. doi: 10.7326/L21-0297. Epub 2021 Nov 16. Ann Intern Med. 2022. PMID: 34781719 Free PMC article.
Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers.
Lian X, Gao C, Sun X, Jiang C, Einkauf KB, Seiger KW, Chevalier JM, Yuki Y, Martin M, Hoh R, Peluso MJ, Carrington M, Ruiz-Mateos E, Deeks SG, Rosenberg ES, Walker BD, Lichterfeld M, Yu XG. Lian X, et al. Sci Transl Med. 2021 Dec 15;13(624):eabl4097. doi: 10.1126/scitranslmed.abl4097. Epub 2021 Dec 15. Sci Transl Med. 2021. PMID: 34910552 Free PMC article.
Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses.
Einkauf KB, Osborn MR, Gao C, Sun W, Sun X, Lian X, Parsons EM, Gladkov GT, Seiger KW, Blackmer JE, Jiang C, Yukl SA, Rosenberg ES, Yu XG, Lichterfeld M. Einkauf KB, et al. Among authors: lian x. Cell. 2022 Jan 20;185(2):266-282.e15. doi: 10.1016/j.cell.2021.12.011. Epub 2022 Jan 12. Cell. 2022. PMID: 35026153 Free PMC article.
Immune correlates of HIV-1 reservoir cell decline in early-treated infants.
Hartana CA, Garcia-Broncano P, Rassadkina Y, Lian X, Jiang C, Einkauf KB, Maswabi K, Ajibola G, Moyo S, Mohammed T, Maphorisa C, Makhema J, Yuki Y, Martin M, Bennett K, Jean-Philippe P, Viard M, Hughes MD, Powis KM, Carrington M, Lockman S, Gao C, Yu XG, Kuritzkes DR, Shapiro R, Lichterfeld M. Hartana CA, et al. Among authors: lian x. Cell Rep. 2022 Jul 19;40(3):111126. doi: 10.1016/j.celrep.2022.111126. Cell Rep. 2022. PMID: 35858580 Free PMC article.
Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy.
Lian X, Seiger KW, Parsons EM, Gao C, Sun W, Gladkov GT, Roseto IC, Einkauf KB, Osborn MR, Chevalier JM, Jiang C, Blackmer J, Carrington M, Rosenberg ES, Lederman MM, McMahon DK, Bosch RJ, Jacobson JM, Gandhi RT, Peluso MJ, Chun TW, Deeks SG, Yu XG, Lichterfeld M. Lian X, et al. Cell Host Microbe. 2023 Jan 11;31(1):83-96.e5. doi: 10.1016/j.chom.2022.12.002. Epub 2023 Jan 2. Cell Host Microbe. 2023. PMID: 36596305 Free PMC article.
Phenotypic signatures of immune selection in HIV-1 reservoir cells.
Sun W, Gao C, Hartana CA, Osborn MR, Einkauf KB, Lian X, Bone B, Bonheur N, Chun TW, Rosenberg ES, Walker BD, Yu XG, Lichterfeld M. Sun W, et al. Among authors: lian x. Nature. 2023 Feb;614(7947):309-317. doi: 10.1038/s41586-022-05538-8. Epub 2023 Jan 4. Nature. 2023. PMID: 36599977 Free PMC article.
1,507 results