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Barcoding intracellular reverse transcription enables high-throughput phenotype-coupled T cell receptor analyses.
Jayaraman S, Montagne JM, Nirschl TR, Marcisak E, Johnson J, Huff A, Hsiao MH, Nauroth J, Heumann T, Zarif JC, Jaffee EM, Azad N, Fertig EJ, Zaidi N, Larman HB. Jayaraman S, et al. Among authors: nirschl tr. Cell Rep Methods. 2023 Oct 23;3(10):100600. doi: 10.1016/j.crmeth.2023.100600. Epub 2023 Sep 29. Cell Rep Methods. 2023. PMID: 37776855 Free PMC article.
TGM4: an immunogenic prostate-restricted antigen.
Lopez-Bujanda ZA, Obradovic A, Nirschl TR, Crowley L, Macedo R, Papachristodoulou A, O'Donnell T, Laserson U, Zarif JC, Reshef R, Yuan T, Soni MK, Antonarakis ES, Haffner MC, Larman HB, Shen MM, Muranski P, Drake CG. Lopez-Bujanda ZA, et al. Among authors: nirschl tr. J Immunother Cancer. 2021 Jun;9(6):e001649. doi: 10.1136/jitc-2020-001649. J Immunother Cancer. 2021. PMID: 34193566 Free PMC article.
High-dimensional Cytometry (ExCYT) and Mass Spectrometry of Myeloid Infiltrate in Clinically Localized Clear Cell Renal Cell Carcinoma Identifies Novel Potential Myeloid Targets for Immunotherapy.
Theodros D, Murter BM, Sidhom JW, Nirschl TR, Clark DJ, Chen L, Tam AJ, Blosser RL, Schwen ZR, Johnson MH, Pierorazio PM, Zhang H, Ganguly S, Pardoll DM, Zarif JC. Theodros D, et al. Among authors: nirschl tr. Mol Cell Proteomics. 2020 Nov;19(11):1850-1859. doi: 10.1074/mcp.RA120.002049. Epub 2020 Jul 31. Mol Cell Proteomics. 2020. PMID: 32737216 Free PMC article.
Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators.
Obradovic A, Ager C, Turunen M, Nirschl T, Khosravi-Maharlooei M, Iuga A, Jackson CM, Yegnasubramanian S, Tomassoni L, Fernandez EC, McCann P, Rogava M, DeMarzo AM, Kochel CM, Allaf M, Bivalacqua T, Lim M, Realubit R, Karan C, Drake CG, Califano A. Obradovic A, et al. Cancer Cell. 2023 May 8;41(5):933-949.e11. doi: 10.1016/j.ccell.2023.04.003. Epub 2023 Apr 27. Cancer Cell. 2023. PMID: 37116491 Free PMC article.
T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer.
Obradovic AZ, Dallos MC, Zahurak ML, Partin AW, Schaeffer EM, Ross AE, Allaf ME, Nirschl TR, Liu D, Chapman CG, O'Neal T, Cao H, Durham JN, Guner G, Baena-Del Valle JA, Ertunc O, De Marzo AM, Antonarakis ES, Drake CG. Obradovic AZ, et al. Among authors: nirschl tr. Clin Cancer Res. 2020 Jul 1;26(13):3182-3192. doi: 10.1158/1078-0432.CCR-19-3372. Epub 2020 Mar 15. Clin Cancer Res. 2020. PMID: 32173650 Free PMC article.
Neoadjuvant Nivolumab in Patients with High-risk Nonmetastatic Renal Cell Carcinoma.
Gorin MA, Patel HD, Rowe SP, Hahn NM, Hammers HJ, Pons A, Trock BJ, Pierorazio PM, Nirschl TR, Salles DC, Stein JE, Lotan TL, Taube JM, Drake CG, Allaf ME. Gorin MA, et al. Among authors: nirschl tr. Eur Urol Oncol. 2022 Feb;5(1):113-117. doi: 10.1016/j.euo.2021.04.002. Epub 2021 May 26. Eur Urol Oncol. 2022. PMID: 34049847 Free PMC article.
Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition.
Mao W, Ghasemzadeh A, Freeman ZT, Obradovic A, Chaimowitz MG, Nirschl TR, McKiernan E, Yegnasubramanian S, Drake CG. Mao W, et al. Among authors: nirschl tr. J Immunother Cancer. 2019 Oct 25;7(1):277. doi: 10.1186/s40425-019-0758-y. J Immunother Cancer. 2019. PMID: 31653272 Free PMC article.
27 results