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A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo.
Giannakopoulou E, Lehander M, Virding Culleton S, Yang W, Li Y, Karpanen T, Yoshizato T, Rustad EH, Nielsen MM, Bollineni RC, Tran TT, Delic-Sarac M, Gjerdingen TJ, Douvlataniotis K, Laos M, Ali M, Hillen A, Mazzi S, Chin DWL, Mehta A, Holm JS, Bentzen AK, Bill M, Griffioen M, Gedde-Dahl T, Lehmann S, Jacobsen SEW, Woll PS, Olweus J. Giannakopoulou E, et al. Among authors: bollineni rc. Nat Cancer. 2023 Oct;4(10):1474-1490. doi: 10.1038/s43018-023-00642-8. Epub 2023 Oct 2. Nat Cancer. 2023. PMID: 37783807 Free PMC article.
A systematic safety pipeline for selection of T-cell receptors to enter clinical use.
Foldvari Z, Knetter C, Yang W, Gjerdingen TJ, Bollineni RC, Tran TT, Lund-Johansen F, Kolstad A, Drousch K, Klopfleisch R, Leisegang M, Olweus J. Foldvari Z, et al. Among authors: bollineni rc. NPJ Vaccines. 2023 Aug 22;8(1):126. doi: 10.1038/s41541-023-00713-y. NPJ Vaccines. 2023. PMID: 37607971 Free PMC article.
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants.
Meyer S, Blaas I, Bollineni RC, Delic-Sarac M, Tran TT, Knetter C, Dai KZ, Madssen TS, Vaage JT, Gustavsen A, Yang W, Nissen-Meyer LSH, Douvlataniotis K, Laos M, Nielsen MM, Thiede B, Søraas A, Lund-Johansen F, Rustad EH, Olweus J. Meyer S, et al. Among authors: bollineni rc. Cell Rep. 2023 Jan 31;42(1):111995. doi: 10.1016/j.celrep.2023.111995. Epub 2023 Jan 9. Cell Rep. 2023. PMID: 36656713 Free PMC article.
Chasing neoantigens; invite naïve T cells to the party.
Bollineni RC, Tran TT, Lund-Johansen F, Olweus J. Bollineni RC, et al. Curr Opin Immunol. 2022 Apr;75:102172. doi: 10.1016/j.coi.2022.102172. Epub 2022 Mar 10. Curr Opin Immunol. 2022. PMID: 35279483 Review.
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.
Ali M, Giannakopoulou E, Li Y, Lehander M, Virding Culleton S, Yang W, Knetter C, Odabasi MC, Bollineni RC, Yang X, Foldvari Z, Böschen ML, Taraldsrud E, Strønen E, Toebes M, Hillen A, Mazzi S, de Ru AH, Janssen GMC, Kolstad A, Tjønnfjord GE, Lie BA, Griffioen M, Lehmann S, Osnes LT, Buechner J, Garcia KC, Schumacher TN, van Veelen PA, Leisegang M, Jacobsen SEW, Woll P, Olweus J. Ali M, et al. Among authors: bollineni rc. Nat Biotechnol. 2022 Apr;40(4):488-498. doi: 10.1038/s41587-021-01089-x. Epub 2021 Dec 6. Nat Biotechnol. 2022. PMID: 34873326 Free PMC article.
18 results