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Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors.
Heppner D, Wittlinger F, Ogboo B, Shevchenko E, Damghani T, Pham C, Schaeffner I, Oligny B, Chitnis S, Beyett T, Rasch A, Buckley B, Urul D, Shaurova T, May E, Schaefer E, Eck M, Hershberger P, Poso A, Laufer S. Heppner D, et al. Among authors: may e. Res Sq [Preprint]. 2023 Sep 13:rs.3.rs-3286949. doi: 10.21203/rs.3.rs-3286949/v1. Res Sq. 2023. PMID: 37790373 Free PMC article. Updated. Preprint.
Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448).
Heppner DE, Wittlinger F, Beyett TS, Shaurova T, Urul DA, Buckley B, Pham CD, Schaeffner IK, Yang B, Ogboo BC, May EW, Schaefer EM, Eck MJ, Laufer SA, Hershberger PA. Heppner DE, et al. Among authors: may ew. ACS Med Chem Lett. 2022 Nov 10;13(12):1856-1863. doi: 10.1021/acsmedchemlett.2c00213. eCollection 2022 Dec 8. ACS Med Chem Lett. 2022. PMID: 36518696 Free PMC article.
Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors.
Wittlinger F, Ogboo BC, Shevchenko E, Damghani T, Pham CD, Schaeffner IK, Oligny BT, Chitnis SP, Beyett TS, Rasch A, Buckley B, Urul DA, Shaurova T, May EW, Schaefer EM, Eck MJ, Hershberger PA, Poso A, Laufer SA, Heppner DE. Wittlinger F, et al. Among authors: may ew. Commun Chem. 2024 Feb 20;7(1):38. doi: 10.1038/s42004-024-01108-3. Commun Chem. 2024. PMID: 38378740 Free PMC article.
Proteomic analysis of Neobenedenia sp. and Rhabdosynochus viridisi (Monogenea, Monopisthocotylea): Insights into potential vaccine targets and diagnostic markers for finfish aquaculture.
Caña-Bozada VH, Huerta-Ocampo JÁ, Bojórquez-Velázquez E, Elizalde-Contreras JM, May ER, Morales-Serna FN. Caña-Bozada VH, et al. Among authors: may er. Vet Parasitol. 2024 May 10;329:110196. doi: 10.1016/j.vetpar.2024.110196. Online ahead of print. Vet Parasitol. 2024. PMID: 38763120
The α C helix is a central regulator of PKR activation.
Feinstein AG, Cole JL, May ER. Feinstein AG, et al. Among authors: may er. bioRxiv [Preprint]. 2024 May 2:2024.04.30.591909. doi: 10.1101/2024.04.30.591909. bioRxiv. 2024. PMID: 38746189 Free PMC article. Preprint.
839 results