Fenton T - Search Results

1

Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1 mutations.

Silverman JL, Fenton T, Haouchine O, Hallam E, Smith E, Jackson K, Rahbarian D, Canales C, Adhikari A, Nord A, Ben-Shalom R. Silverman JL, et al. Among authors: fenton t. Res Sq [Preprint]. 2023 Sep 13:rs.3.rs-3246655. doi: 10.21203/rs.3.rs-3246655/v1. Res Sq. 2023. PMID: 37790402 Free PMC article. Preprint.

2

Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome.

Berg EL, Pride MC, Petkova SP, Lee RD, Copping NA, Shen Y, Adhikari A, Fenton TA, Pedersen LR, Noakes LS, Nieman BJ, Lerch JP, Harris S, Born HA, Peters MM, Deng P, Cameron DL, Fink KD, Beitnere U, O'Geen H, Anderson AE, Dindot SV, Nash KR, Weeber EJ, Wöhr M, Ellegood J, Segal DJ, Silverman JL. Berg EL, et al. Among authors: fenton ta. Transl Psychiatry. 2020 Jan 27;10(1):39. doi: 10.1038/s41398-020-0720-2. Transl Psychiatry. 2020. PMID: 32066685 Free PMC article.

3

Cyclin D2-knock-out mice with attenuated dentate gyrus neurogenesis have robust deficits in long-term memory formation.

Petkova SP, Pride M, Klocke C, Fenton TA, White J, Lein PJ, Ellegood J, Lerch JP, Silverman JL, Waldau B. Petkova SP, et al. Sci Rep. 2020 May 18;10(1):8204. doi: 10.1038/s41598-020-65090-1. Sci Rep. 2020. PMID: 32424171 Free PMC article.

4

Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice.

Haigh JL, Adhikari A, Copping NA, Stradleigh T, Wade AA, Catta-Preta R, Su-Feher L, Zdilar I, Morse S, Fenton TA, Nguyen A, Quintero D, Agezew S, Sramek M, Kreun EJ, Carter J, Gompers A, Lambert JT, Canales CP, Pennacchio LA, Visel A, Dickel DE, Silverman JL, Nord AS. Haigh JL, et al. Among authors: fenton ta. Genome Med. 2021 Apr 26;13(1):69. doi: 10.1186/s13073-021-00884-0. Genome Med. 2021. PMID: 33910599 Free PMC article.

5

Excessive Laughter-like Vocalizations, Microcephaly, and Translational Outcomes in the Ube3a Deletion Rat Model of Angelman Syndrome.

Berg EL, Jami SA, Petkova SP, Berz A, Fenton TA, Lerch JP, Segal DJ, Gray JA, Ellegood J, Wöhr M, Silverman JL. Berg EL, et al. J Neurosci. 2021 Oct 20;41(42):8801-8814. doi: 10.1523/JNEUROSCI.0925-21.2021. Epub 2021 Sep 2. J Neurosci. 2021. PMID: 34475199 Free PMC article.

6

Gait as a quantitative translational outcome measure in Angelman syndrome.

Petkova SP, Adhikari A, Berg EL, Fenton TA, Duis J, Silverman JL. Petkova SP, et al. Autism Res. 2022 May;15(5):821-833. doi: 10.1002/aur.2697. Epub 2022 Mar 10. Autism Res. 2022. PMID: 35274462 Free PMC article.

7

Touchscreen cognitive deficits, hyperexcitability and hyperactivity in males and females using two models of Cdkl5 deficiency.

Adhikari A, Buchanan FKB, Fenton TA, Cameron DL, Halmai JANM, Copping NA, Fink KD, Silverman JL. Adhikari A, et al. Hum Mol Genet. 2022 Sep 10;31(18):3032-3050. doi: 10.1093/hmg/ddac091. Hum Mol Genet. 2022. PMID: 35445702 Free PMC article.

8

Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model.

O'Geen H, Beitnere U, Garcia MS, Adhikari A, Cameron DL, Fenton TA, Copping NA, Deng P, Lock S, Halmai JANM, Villegas IJ, Liu J, Wang D, Fink KD, Silverman JL, Segal DJ. O'Geen H, et al. Mol Ther. 2023 Apr 5;31(4):1088-1105. doi: 10.1016/j.ymthe.2023.01.013. Epub 2023 Jan 14. Mol Ther. 2023. PMID: 36641623 Free PMC article.

9

Hyperexcitability and translational phenotypes in a preclinical model of SYNGAP1 mutations.

Fenton TA, Haouchine OY, Hallam EL, Smith EM, Jackson KC, Rahbarian D, Canales C, Adhikari A, Nord AS, Ben-Shalom R, Silverman JL. Fenton TA, et al. bioRxiv [Preprint]. 2023 Jul 26:2023.07.24.550093. doi: 10.1101/2023.07.24.550093. bioRxiv. 2023. PMID: 37546838 Free PMC article. Preprint.

10

Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy.

Quinn S, Zhang N, Fenton TA, Brusel M, Muruganandam P, Peleg Y, Giladi M, Haitin Y, Lerche H, Bassan H, Liu Y, Ben-Shalom R, Rubinstein M. Quinn S, et al. Among authors: fenton ta. Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167127. doi: 10.1016/j.bbadis.2024.167127. Epub 2024 Mar 20. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38519006 Free article.

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