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A transgenic mice model of retinopathy of cblG-type inherited disorder of one-carbon metabolism highlights epigenome-wide alterations related to cone photoreceptor cells development and retinal metabolism.
Matmat K, Conart JB, Graindorge PH, El Kouche S, Hassan Z, Siblini Y, Umoret R, Safar R, Baspinar O, Robert A, Alberto JM, Oussalah A, Coelho D, Guéant JL, Guéant-Rodriguez RM. Matmat K, et al. Among authors: umoret r. Clin Epigenetics. 2023 Oct 5;15(1):158. doi: 10.1186/s13148-023-01567-w. Clin Epigenetics. 2023. PMID: 37798757 Free PMC article.
Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.
Battaglia-Hsu SF, Ghemrawi R, Coelho D, Dreumont N, Mosca P, Hergalant S, Gauchotte G, Sequeira JM, Ndiongue M, Houlgatte R, Alberto JM, Umoret R, Robert A, Paoli J, Jung M, Quadros EV, Guéant JL. Battaglia-Hsu SF, et al. Among authors: umoret r. Nucleic Acids Res. 2018 Sep 6;46(15):7844-7857. doi: 10.1093/nar/gky634. Nucleic Acids Res. 2018. PMID: 30016500 Free PMC article.
Folate and Cobalamin Deficiencies during Pregnancy Disrupt the Glucocorticoid Response in Hypothalamus through N-Homocysteinilation of the Glucocorticoid Receptor.
Michel A, Kokten T, Saber-Cherif L, Umoret R, Alberto JM, Helle D, Julien A, Daval JL, Guéant JL, Bossenmeyer-Pourié C, Pourié G. Michel A, et al. Among authors: umoret r. Int J Mol Sci. 2023 Jun 7;24(12):9847. doi: 10.3390/ijms24129847. Int J Mol Sci. 2023. PMID: 37372992 Free PMC article.
15 results