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327 results

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Page 1
Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease.
Hung AM, Assimon VA, Chen HC, Yu Z, Vlasschaert C, Triozzi JL, Chan H, Wheless L, Wilson O, Shah SC, Mack T, Thompson T, Matheny ME, Chandrasekar S, Mozaffari SV, Chung CP, Tsao P, Susztak K, Siew ED, Estrada K, Gaziano JM, Graham RR, Tao R, Hoek M, Robinson-Cohen C, Green EM, Bick AG; Million Veteran Program. Hung AM, et al. Among authors: mack t. J Am Soc Nephrol. 2023 Nov 1;34(11):1889-1899. doi: 10.1681/ASN.0000000000000219. Epub 2023 Oct 6. J Am Soc Nephrol. 2023. PMID: 37798822
Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.
Yu Z, Fidler TP, Ruan Y, Vlasschaert C, Nakao T, Uddin MM, Mack T, Niroula A, Heimlich JB, Zekavat SM, Gibson CJ, Griffin GK, Wang Y, Peloso GM, Heard-Costa N, Levy D, Vasan RS, Aguet F, Ardlie KG, Taylor KD, Rich SS, Rotter JI, Libby P, Jaiswal S, Ebert BL, Bick AG, Tall AR, Natarajan P. Yu Z, et al. Among authors: mack t. J Clin Invest. 2023 Sep 15;133(18):e168597. doi: 10.1172/JCI168597. J Clin Invest. 2023. PMID: 37498674 Free PMC article.
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk.
Kishtagari A, Khan MAW, Li Y, Vlasschaert C, Marneni N, Silver AJ, von Beck K, Spaulding T, Stockton S, Snider C, Sochacki A, Dorand D, Mack TM, Ferrell PB Jr, Xu Y, Bejan CA, Savona MR, Bick AG. Kishtagari A, et al. Among authors: mack tm. Blood Cancer J. 2024 Jan 15;14(1):6. doi: 10.1038/s41408-023-00974-9. Blood Cancer J. 2024. PMID: 38225345 Free PMC article.
Cost-Effective and Scalable Clonal Hematopoiesis Assay Provides Insight into Clonal Dynamics.
Mack T, Vlasschaert C, von Beck K, Silver AJ, Heimlich JB, Poisner H, Condon HR, Ulloa J, Sochacki AL, Spaulding TP, Kishtagari A, Bejan CA, Xu Y, Savona MR, Jones A, Bick AG. Mack T, et al. J Mol Diagn. 2024 Apr 6:S1525-1578(24)00076-X. doi: 10.1016/j.jmoldx.2024.03.007. Online ahead of print. J Mol Diagn. 2024. PMID: 38588769 Free article.
Cost-effective and scalable clonal hematopoiesis assay provides insight into clonal dynamics.
Mack T, Vlasschaert C, von Beck K, Silver AJ, Heimlich JB, Poisner H, Condon HR, Ulloa J, Sochacki AL, Spaulding TP, Kishtagari A, Bejan CA, Xu Y, Savona MR, Jones A, Bick A. Mack T, et al. medRxiv [Preprint]. 2023 Nov 9:2023.11.08.23298270. doi: 10.1101/2023.11.08.23298270. medRxiv. 2023. PMID: 37986782 Free PMC article. Updated. Preprint.
Determinants of mosaic chromosomal alteration fitness.
Pershad Y, Mack T, Poisner H, Jakubek YA, Stilp AM, Mitchell BD, Lewis JP, Boerwinkle E, Loos RJF, Chami N, Wang Z, Barnes K, Pankratz N, Fornage M, Redline S, Psaty BM, Bis JC, Shojaie A, Silverman EK, Cho MH, Yun JH, DeMeo D, Levy D, Johnson AD, Mathias RA, Taub MA, Arnett D, North KE, Raffield LM, Carson AP, Doyle MF, Rich SS, Rotter JI, Guo X, Cox NJ, Roden DM, Franceschini N, Desai P, Reiner AP, Auer PL, Scheet PA, Jaiswal S, Weinstock JS, Bick AG. Pershad Y, et al. Among authors: mack t. Nat Commun. 2024 May 7;15(1):3800. doi: 10.1038/s41467-024-48190-8. Nat Commun. 2024. PMID: 38714703 Free PMC article.
Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing.
Jakubek YA, Zhou Y, Stilp A, Bacon J, Wong JW, Ozcan Z, Arnett D, Barnes K, Bis JC, Boerwinkle E, Brody JA, Carson AP, Chasman DI, Chen J, Cho M, Conomos MP, Cox N, Doyle MF, Fornage M, Guo X, Kardia SLR, Lewis JP, Loos RJF, Ma X, Machiela MJ, Mack TM, Mathias RA, Mitchell BD, Mychaleckyj JC, North K, Pankratz N, Peyser PA, Preuss MH, Psaty B, Raffield LM, Vasan RS, Redline S, Rich SS, Rotter JI, Silverman EK, Smith JA, Smith AP, Taub M, Taylor KD, Yun J, Li Y, Desai P, Bick AG, Reiner AP, Scheet P, Auer PL. Jakubek YA, et al. Nat Genet. 2023 Nov;55(11):1912-1919. doi: 10.1038/s41588-023-01553-1. Epub 2023 Oct 30. Nat Genet. 2023. PMID: 37904051 Free PMC article.
327 results