Waters AP - Search Results

1

A conserved metabolic signature associated with response to fast-acting anti-malarial agents.

Simwela NV, Guiguemde WA, Straimer J, Regnault C, Stokes BH, Tavernelli LE, Yokokawa F, Taft B, Diagana TT, Barrett MP, Waters AP. Simwela NV, et al. Among authors: waters ap. Microbiol Spectr. 2023 Dec 12;11(6):e0397622. doi: 10.1128/spectrum.03976-22. Epub 2023 Oct 6. Microbiol Spectr. 2023. PMID: 37800971 Free PMC article.

2

Plasmodium berghei K13 Mutations Mediate In Vivo Artemisinin Resistance That Is Reversed by Proteasome Inhibition.

Simwela NV, Stokes BH, Aghabi D, Bogyo M, Fidock DA, Waters AP. Simwela NV, et al. Among authors: waters ap. mBio. 2020 Nov 10;11(6):e02312-20. doi: 10.1128/mBio.02312-20. mBio. 2020. PMID: 33173001 Free PMC article.

3

Mammalian Deubiquitinating Enzyme Inhibitors Display in Vitro and in Vivo Activity against Malaria Parasites and Potentiate Artemisinin Action.

Simwela NV, Hughes KR, Rennie MT, Barrett MP, Waters AP. Simwela NV, et al. Among authors: waters ap. ACS Infect Dis. 2021 Feb 12;7(2):333-346. doi: 10.1021/acsinfecdis.0c00580. Epub 2021 Jan 5. ACS Infect Dis. 2021. PMID: 33400499

4

Current status of experimental models for the study of malaria.

Simwela NV, Waters AP. Simwela NV, et al. Among authors: waters ap. Parasitology. 2022 Feb 21;149(6):1-22. doi: 10.1017/S0031182021002134. Online ahead of print. Parasitology. 2022. PMID: 35357277 Free PMC article. Review.

5

Experimentally Engineered Mutations in a Ubiquitin Hydrolase, UBP-1, Modulate In Vivo Susceptibility to Artemisinin and Chloroquine in Plasmodium berghei.

Simwela NV, Hughes KR, Roberts AB, Rennie MT, Barrett MP, Waters AP. Simwela NV, et al. Among authors: waters ap. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e02484-19. doi: 10.1128/AAC.02484-19. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32340987 Free PMC article.

6

Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments.

Srivastava A, Philip N, Hughes KR, Georgiou K, MacRae JI, Barrett MP, Creek DJ, McConville MJ, Waters AP. Srivastava A, et al. Among authors: waters ap. PLoS Pathog. 2016 Dec 27;12(12):e1006094. doi: 10.1371/journal.ppat.1006094. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 28027318 Free PMC article.

7

Host reticulocytes provide metabolic reservoirs that can be exploited by malaria parasites.

Srivastava A, Creek DJ, Evans KJ, De Souza D, Schofield L, Müller S, Barrett MP, McConville MJ, Waters AP. Srivastava A, et al. Among authors: waters ap. PLoS Pathog. 2015 Jun 4;11(6):e1004882. doi: 10.1371/journal.ppat.1004882. eCollection 2015 Jun. PLoS Pathog. 2015. PMID: 26042734 Free PMC article.

8

Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target.

Alam MM, Sanchez-Azqueta A, Janha O, Flannery EL, Mahindra A, Mapesa K, Char AB, Sriranganadane D, Brancucci NMB, Antonova-Koch Y, Crouch K, Simwela NV, Millar SB, Akinwale J, Mitcheson D, Solyakov L, Dudek K, Jones C, Zapatero C, Doerig C, Nwakanma DC, Vázquez MJ, Colmenarejo G, Lafuente-Monasterio MJ, Leon ML, Godoi PHC, Elkins JM, Waters AP, Jamieson AG, Álvaro EF, Ranford-Cartwright LC, Marti M, Winzeler EA, Gamo FJ, Tobin AB. Alam MM, et al. Among authors: waters ap. Science. 2019 Aug 30;365(6456):eaau1682. doi: 10.1126/science.aau1682. Science. 2019. PMID: 31467193 Free article.

9

Drug resistance in eukaryotic microorganisms.

Fairlamb AH, Gow NA, Matthews KR, Waters AP. Fairlamb AH, et al. Among authors: waters ap. Nat Microbiol. 2016 Jun 24;1(7):16092. doi: 10.1038/nmicrobiol.2016.92. Nat Microbiol. 2016. PMID: 27572976 Free PMC article. Review.

10

Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium berghei.

Kent RS, Modrzynska KK, Cameron R, Philip N, Billker O, Waters AP. Kent RS, et al. Among authors: waters ap. Nat Microbiol. 2018 Nov;3(11):1206-1213. doi: 10.1038/s41564-018-0223-6. Epub 2018 Sep 3. Nat Microbiol. 2018. PMID: 30177743 Free PMC article.

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