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TCF-1 limits intraepithelial lymphocyte antitumor immunity in colorectal carcinoma.
Yakou MH, Ghilas S, Tran K, Liao Y, Afshar-Sterle S, Kumari A, Schmid K, Dijkstra C, Inguanti C, Ostrouska S, Wilcox J, Smith M, Parathan P, Allam A, Xue HH, Belz GT, Mariadason JM, Behren A, Drummond GR, Ruscher R, Williams DS, Pal B, Shi W, Ernst M, Raghu D, Mielke LA. Yakou MH, et al. Among authors: xue hh. Sci Immunol. 2023 Oct 13;8(88):eadf2163. doi: 10.1126/sciimmunol.adf2163. Epub 2023 Oct 6. Sci Immunol. 2023. PMID: 37801516
TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis.
Mielke LA, Liao Y, Clemens EB, Firth MA, Duckworth B, Huang Q, Almeida FF, Chopin M, Koay HF, Bell CA, Hediyeh-Zadeh S, Park SL, Raghu D, Choi J, Putoczki TL, Hodgkin PD, Franks AE, Mackay LK, Godfrey DI, Davis MJ, Xue HH, Bryant VL, Kedzierska K, Shi W, Belz GT. Mielke LA, et al. Among authors: xue hh. J Exp Med. 2019 Jul 1;216(7):1682-1699. doi: 10.1084/jem.20181778. Epub 2019 May 29. J Exp Med. 2019. PMID: 31142588 Free PMC article.
Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity.
Goldman N, Chandra A, Johnson I, Sullivan MA, Patil AR, Vanderbeck A, Jay A, Zhou Y, Ferrari EK, Mayne L, Aguilan J, Xue HH, Faryabi RB, John Wherry E, Sidoli S, Maillard I, Vahedi G. Goldman N, et al. Among authors: xue hh. Nat Immunol. 2023 Oct;24(10):1698-1710. doi: 10.1038/s41590-023-01599-7. Epub 2023 Aug 17. Nat Immunol. 2023. PMID: 37592014 Free PMC article.
TCF1 in T cell immunity: a broadened frontier.
Zhao X, Shan Q, Xue HH. Zhao X, et al. Among authors: xue hh. Nat Rev Immunol. 2022 Mar;22(3):147-157. doi: 10.1038/s41577-021-00563-6. Epub 2021 Jun 14. Nat Rev Immunol. 2022. PMID: 34127847 Review.
The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity.
Gautam S, Fioravanti J, Zhu W, Le Gall JB, Brohawn P, Lacey NE, Hu J, Hocker JD, Hawk NV, Kapoor V, Telford WG, Gurusamy D, Yu Z, Bhandoola A, Xue HH, Roychoudhuri R, Higgs BW, Restifo NP, Bender TP, Ji Y, Gattinoni L. Gautam S, et al. Among authors: xue hh. Nat Immunol. 2019 Mar;20(3):337-349. doi: 10.1038/s41590-018-0311-z. Epub 2019 Feb 18. Nat Immunol. 2019. PMID: 30778251 Free PMC article.
Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria.
Vijay R, Guthmiller JJ, Sturtz AJ, Surette FA, Rogers KJ, Sompallae RR, Li F, Pope RL, Chan JA, de Labastida Rivera F, Andrew D, Webb L, Maury WJ, Xue HH, Engwerda CR, McCarthy JS, Boyle MJ, Butler NS. Vijay R, et al. Among authors: xue hh. Nat Immunol. 2020 Jul;21(7):790-801. doi: 10.1038/s41590-020-0678-5. Epub 2020 May 18. Nat Immunol. 2020. PMID: 32424361 Free PMC article. Clinical Trial.
123 results