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Page 1
Preclinical development of humanized monoclonal antibodies against CD169 as a broad antiviral therapeutic strategy.
Resa-Infante P, Erkizia I, Muñiz-Trabudua X, Linty F, Bentlage AEH, Perez-Zsolt D, Muñoz-Basagoiti J, Raïch-Regué D, Izquierdo-Useros N, Rispens T, Vidarsson G, Martinez-Picado J. Resa-Infante P, et al. Among authors: bentlage aeh. Biomed Pharmacother. 2024 May 15;175:116726. doi: 10.1016/j.biopha.2024.116726. Online ahead of print. Biomed Pharmacother. 2024. PMID: 38754263 Free article.
IgG hexamers initiate complement-dependent acute lung injury.
Cleary SJ, Seo Y, Tian JJ, Kwaan N, Bulkley DP, Bentlage AEH, Vidarsson G, Boilard É, Spirig R, Zimring JC, Looney MR. Cleary SJ, et al. Among authors: bentlage aeh. J Clin Invest. 2024 Mar 26:e178351. doi: 10.1172/JCI178351. Online ahead of print. J Clin Invest. 2024. PMID: 38530369 Free article.
IgG hexamers initiate acute lung injury.
Cleary SJ, Seo Y, Tian JJ, Kwaan N, Bulkley DP, Bentlage AEH, Vidarsson G, Boilard É, Spirig R, Zimring JC, Looney MR. Cleary SJ, et al. Among authors: bentlage aeh. bioRxiv [Preprint]. 2024 Jan 27:2024.01.24.577129. doi: 10.1101/2024.01.24.577129. bioRxiv. 2024. PMID: 38328049 Free PMC article. Updated. Preprint.
Cellular surface plasmon resonance-based detection of anti-HPA-1a antibody glycosylation in fetal and neonatal alloimmune thrombocytopenia.
Szittner Z, Bentlage AEH, Temming AR, Schmidt DE, Visser R, Lissenberg-Thunnissen S, Mok JY, van Esch WJE, Sonneveld ME, de Graaf EL, Wuhrer M, Porcelijn L, de Haas M, van der Schoot CE, Vidarsson G. Szittner Z, et al. Among authors: bentlage aeh. Front Immunol. 2023 Oct 5;14:1225603. doi: 10.3389/fimmu.2023.1225603. eCollection 2023. Front Immunol. 2023. PMID: 37868955 Free PMC article.
Formation and clearance of TNF-TNF inhibitor complexes during TNF inhibitor treatment.
Berkhout LC, I'Ami MJ, Kruithof S, Vogelzang EH, Hooijberg F, Hart MHL, Bentlage AEH, Thomas D, Vermeire S, Vidarsson G, Ten Brinke A, Nurmohamed MT, Wolbink GJ, Rispens T. Berkhout LC, et al. Among authors: bentlage aeh. Br J Pharmacol. 2024 Apr;181(8):1165-1181. doi: 10.1111/bph.16269. Epub 2023 Dec 5. Br J Pharmacol. 2024. PMID: 37859583
Complement activation drives antibody-mediated transfusion-related acute lung injury via macrophage trafficking and formation of NETs.
van der Velden S, van Osch TLJ, Seghier A, Bentlage AEH, Mok JY, Geerdes DM, van Esch WJE, Pouw RB, Brouwer MC, Jongerius I, de Haas M, Porcelijn L, van der Schoot CE, Vidarsson G, Kapur R. van der Velden S, et al. Among authors: bentlage aeh. Blood. 2024 Jan 4;143(1):79-91. doi: 10.1182/blood.2023020484. Blood. 2024. PMID: 37801721
Corrigendum: Anti-HIV-1 nanobody-IgG1 constructs with improved neutralization potency and the ability to mediate Fc effector functions.
Schriek AI, van Haaren MM, Poniman M, Dekkers G, Bentlage AEH, Grobben M, Vidarsson G, Sanders RW, Verrips T, Geijtenbeek TBH, Heukers R, Kootstra NA, de Taeye SW, van Gils MJ. Schriek AI, et al. Among authors: bentlage aeh. Front Immunol. 2022 Nov 22;13:1091668. doi: 10.3389/fimmu.2022.1091668. eCollection 2022. Front Immunol. 2022. PMID: 36483568 Free PMC article.
IgG Fab Glycans Hinder FcRn-Mediated Placental Transport.
Volkov M, Brinkhaus M, van Schie KA, Bondt A, Kissel T, van der Kooi EJ, Bentlage AEH, Koeleman CAM, de Taeye SW, Derksen NI, Dolhain RJEM, Braig-Scherer U, Huizinga TWJ, Wuhrer M, Toes REM, Vidarsson G, van der Woude D. Volkov M, et al. Among authors: bentlage aeh. J Immunol. 2023 Jan 15;210(2):158-167. doi: 10.4049/jimmunol.2200438. J Immunol. 2023. PMID: 36480251
The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement.
Brinkhaus M, Pannecoucke E, van der Kooi EJ, Bentlage AEH, Derksen NIL, Andries J, Balbino B, Sips M, Ulrichts P, Verheesen P, de Haard H, Rispens T, Savvides SN, Vidarsson G. Brinkhaus M, et al. Among authors: bentlage aeh. Nat Commun. 2022 Oct 14;13(1):6073. doi: 10.1038/s41467-022-33764-1. Nat Commun. 2022. PMID: 36241613 Free PMC article.
45 results