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Complement activation drives antibody-mediated transfusion-related acute lung injury via macrophage trafficking and formation of NETs.
van der Velden S, van Osch TLJ, Seghier A, Bentlage AEH, Mok JY, Geerdes DM, van Esch WJE, Pouw RB, Brouwer MC, Jongerius I, de Haas M, Porcelijn L, van der Schoot CE, Vidarsson G, Kapur R. van der Velden S, et al. Among authors: van esch wje. Blood. 2024 Jan 4;143(1):79-91. doi: 10.1182/blood.2023020484. Blood. 2024. PMID: 37801721
Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities.
Dekkers G, Treffers L, Plomp R, Bentlage AEH, de Boer M, Koeleman CAM, Lissenberg-Thunnissen SN, Visser R, Brouwer M, Mok JY, Matlung H, van den Berg TK, van Esch WJE, Kuijpers TW, Wouters D, Rispens T, Wuhrer M, Vidarsson G. Dekkers G, et al. Among authors: van esch wje, van den berg tk. Front Immunol. 2017 Aug 2;8:877. doi: 10.3389/fimmu.2017.00877. eCollection 2017. Front Immunol. 2017. PMID: 28824618 Free PMC article.
Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge.
Stapleton NM, Brinkhaus M, Armour KL, Bentlage AEH, de Taeye SW, Temming AR, Mok JY, Brasser G, Maas M, van Esch WJE, Clark MR, Williamson LM, van der Schoot CE, Vidarsson G. Stapleton NM, et al. Among authors: van esch wje, van der schoot ce. Sci Rep. 2019 May 14;9(1):7363. doi: 10.1038/s41598-019-40731-2. Sci Rep. 2019. PMID: 31089170 Free PMC article.
Discovery and Selection of Hepatitis B Virus-Derived T Cell Epitopes for Global Immunotherapy Based on Viral Indispensability, Conservation, and HLA-Binding Strength.
de Beijer MTA, Jansen DTSL, Dou Y, van Esch WJE, Mok JY, Maas MJP, Brasser G, de Man RA, Woltman AM, Buschow SI. de Beijer MTA, et al. Among authors: van esch wje. J Virol. 2020 Mar 17;94(7):e01663-19. doi: 10.1128/JVI.01663-19. Print 2020 Mar 17. J Virol. 2020. PMID: 31852786 Free PMC article.
Biological and structural characterization of murine TRALI antibody reveals increased Fc-mediated complement activation.
Zeeuw van der Laan EAN, van der Velden S, Bentlage AEH, Larsen MD, van Osch TLJ, Mok JY, Brasser G, Geerdes DM, Koeleman CAM, Nouta J, Semple JW, Porcelijn L, van Esch WJE, Wuhrer M, van der Schoot CE, Vidarsson G, Kapur R. Zeeuw van der Laan EAN, et al. Among authors: van esch wje, van der velden s, van osch tlj, van der schoot ce. Blood Adv. 2020 Aug 25;4(16):3875-3885. doi: 10.1182/bloodadvances.2020002291. Blood Adv. 2020. PMID: 32810222 Free PMC article.
30 results