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Metabolic support by macrophages sustains colonic epithelial homeostasis.
Fritsch SD, Sukhbaatar N, Gonzales K, Sahu A, Tran L, Vogel A, Mazic M, Wilson JL, Forisch S, Mayr H, Oberle R, Weiszmann J, Brenner M, Vanhoutte R, Hofmann M, Pirnes-Karhu S, Magnes C, Kühnast T, Weckwerth W, Bock C, Klavins K, Hengstschläger M, Moissl-Eichinger C, Schabbauer G, Egger G, Pirinen E, Verhelst SHL, Weichhart T. Fritsch SD, et al. Among authors: pirinen e. Cell Metab. 2023 Nov 7;35(11):1931-1943.e8. doi: 10.1016/j.cmet.2023.09.010. Epub 2023 Oct 6. Cell Metab. 2023. PMID: 37804836 Free article.
The activation of hepatic and muscle polyamine catabolism improves glucose homeostasis.
Koponen T, Cerrada-Gimenez M, Pirinen E, Hohtola E, Paananen J, Vuohelainen S, Tusa M, Pirnes-Karhu S, Heikkinen S, Virkamäki A, Uimari A, Alhonen L, Laakso M. Koponen T, et al. Among authors: pirinen e. Amino Acids. 2012 Feb;42(2-3):427-40. doi: 10.1007/s00726-011-1013-0. Epub 2011 Aug 4. Amino Acids. 2012. PMID: 21814795
Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions.
Forsström S, Jackson CB, Carroll CJ, Kuronen M, Pirinen E, Pradhan S, Marmyleva A, Auranen M, Kleine IM, Khan NA, Roivainen A, Marjamäki P, Liljenbäck H, Wang L, Battersby BJ, Richter U, Velagapudi V, Nikkanen J, Euro L, Suomalainen A. Forsström S, et al. Among authors: pirinen e. Cell Metab. 2019 Dec 3;30(6):1040-1054.e7. doi: 10.1016/j.cmet.2019.08.019. Epub 2019 Sep 12. Cell Metab. 2019. PMID: 31523008 Free article.
Mitochondrial sirtuins and metabolic homeostasis.
Pirinen E, Lo Sasso G, Auwerx J. Pirinen E, et al. Best Pract Res Clin Endocrinol Metab. 2012 Dec;26(6):759-70. doi: 10.1016/j.beem.2012.05.001. Epub 2012 May 31. Best Pract Res Clin Endocrinol Metab. 2012. PMID: 23168278 Free PMC article. Review.
Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.
Pirinen E, Cantó C, Jo YS, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K, Auwerx J. Pirinen E, et al. Cell Metab. 2014 Jun 3;19(6):1034-41. doi: 10.1016/j.cmet.2014.04.002. Epub 2014 May 8. Cell Metab. 2014. PMID: 24814482 Free PMC article.
Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy.
Pirinen E, Auranen M, Khan NA, Brilhante V, Urho N, Pessia A, Hakkarainen A, Kuula J, Heinonen U, Schmidt MS, Haimilahti K, Piirilä P, Lundbom N, Taskinen MR, Brenner C, Velagapudi V, Pietiläinen KH, Suomalainen A. Pirinen E, et al. Cell Metab. 2020 Jun 2;31(6):1078-1090.e5. doi: 10.1016/j.cmet.2020.04.008. Epub 2020 May 7. Cell Metab. 2020. PMID: 32386566 Free article.
Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans.
U-Din M, de Mello VD, Tuomainen M, Raiko J, Niemi T, Fromme T, Klåvus A, Gautier N, Haimilahti K, Lehtonen M, Kristiansen K, Newman JW, Pietiläinen KH, Pihlajamäki J, Amri EZ, Klingenspor M, Nuutila P, Pirinen E, Hanhineva K, Virtanen KA. U-Din M, et al. Among authors: pirinen e. Cell Rep. 2023 Sep 26;42(9):113131. doi: 10.1016/j.celrep.2023.113131. Epub 2023 Sep 13. Cell Rep. 2023. PMID: 37708023 Free article.
66 results