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Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.
Radzishevsky I, Odeh M, Bodner O, Zubedat S, Shaulov L, Litvak M, Esaki K, Yoshikawa T, Agranovich B, Li WH, Radzishevsky A, Gottlieb E, Avital A, Wolosker H. Radzishevsky I, et al. Among authors: yoshikawa t. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2302780120. doi: 10.1073/pnas.2302780120. Epub 2023 Oct 9. Proc Natl Acad Sci U S A. 2023. PMID: 37812701 Free PMC article.
ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment.
Kaplan E, Zubedat S, Radzishevsky I, Valenta AC, Rechnitz O, Sason H, Sajrawi C, Bodner O, Konno K, Esaki K, Derdikman D, Yoshikawa T, Watanabe M, Kennedy RT, Billard JM, Avital A, Wolosker H. Kaplan E, et al. Among authors: yoshikawa t. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9628-9633. doi: 10.1073/pnas.1722677115. Epub 2018 Sep 5. Proc Natl Acad Sci U S A. 2018. PMID: 30185558 Free PMC article.
A potential role of fatty acid binding protein 4 in the pathophysiology of autism spectrum disorder.
Maekawa M, Ohnishi T, Toyoshima M, Shimamoto-Mitsuyama C, Hamazaki K, Balan S, Wada Y, Esaki K, Takagai S, Tsuchiya KJ, Nakamura K, Iwata Y, Nara T, Iwayama Y, Toyota T, Nozaki Y, Ohba H, Watanabe A, Hisano Y, Matsuoka S, Tsujii M, Mori N, Matsuzaki H, Yoshikawa T. Maekawa M, et al. Among authors: yoshikawa t. Brain Commun. 2020 Sep 10;2(2):fcaa145. doi: 10.1093/braincomms/fcaa145. eCollection 2020. Brain Commun. 2020. PMID: 33225276 Free PMC article.
Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia.
Yamada K, Gerber DJ, Iwayama Y, Ohnishi T, Ohba H, Toyota T, Aruga J, Minabe Y, Tonegawa S, Yoshikawa T. Yamada K, et al. Among authors: yoshikawa t. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2815-20. doi: 10.1073/pnas.0610765104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360599 Free PMC article.
Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHTM2 and WIZ, in Japanese autism subjects.
Balan S, Iwayama Y, Maekawa M, Toyota T, Ohnishi T, Toyoshima M, Shimamoto C, Esaki K, Yamada K, Iwata Y, Suzuki K, Ide M, Ota M, Fukuchi S, Tsujii M, Mori N, Shinkai Y, Yoshikawa T. Balan S, et al. Among authors: yoshikawa t. Mol Autism. 2014 Oct 6;5(1):49. doi: 10.1186/2040-2392-5-49. eCollection 2014. Mol Autism. 2014. PMID: 25400900 Free PMC article.
Investigation of betaine as a novel psychotherapeutic for schizophrenia.
Ohnishi T, Balan S, Toyoshima M, Maekawa M, Ohba H, Watanabe A, Iwayama Y, Fujita Y, Tan Y, Hisano Y, Shimamoto-Mitsuyama C, Nozaki Y, Esaki K, Nagaoka A, Matsumoto J, Hino M, Mataga N, Hayashi-Takagi A, Hashimoto K, Kunii Y, Kakita A, Yabe H, Yoshikawa T. Ohnishi T, et al. Among authors: yoshikawa t. EBioMedicine. 2019 Jul;45:432-446. doi: 10.1016/j.ebiom.2019.05.062. Epub 2019 Jun 26. EBioMedicine. 2019. PMID: 31255657 Free PMC article.
Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation.
Ma M, Ren Q, Yang J, Zhang K, Xiong Z, Ishima T, Pu Y, Hwang SH, Toyoshima M, Iwayama Y, Hisano Y, Yoshikawa T, Hammock BD, Hashimoto K. Ma M, et al. Among authors: yoshikawa t. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7083-7088. doi: 10.1073/pnas.1819234116. Epub 2019 Mar 19. Proc Natl Acad Sci U S A. 2019. PMID: 30890645 Free PMC article.
4,697 results