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Intravenous Bacille Calmette-Guérin vaccination protects simian immunodeficiency virus-infected macaques from tuberculosis.
Larson EC, Ellis-Connell AL, Rodgers MA, Gubernat AK, Gleim JL, Moriarty RV, Balgeman AJ, Ameel CL, Jauro S, Tomko JA, Kracinovsky KB, Maiello P, Borish HJ, White AG, Klein E, Bucsan AN, Darrah PA, Seder RA, Roederer M, Lin PL, Flynn JL, O'Connor SL, Scanga CA. Larson EC, et al. Among authors: bucsan an. Nat Microbiol. 2023 Nov;8(11):2080-2092. doi: 10.1038/s41564-023-01503-x. Epub 2023 Oct 9. Nat Microbiol. 2023. PMID: 37814073 Free PMC article.
Airway T cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques.
Darrah PA, Zeppa JJ, Wang C, Irvine EB, Bucsan AN, Rodgers MA, Pokkali S, Hackney JA, Kamath M, White AG, Borish HJ, Frye LJ, Tomko J, Kracinovsky K, Lin PL, Klein E, Scanga CA, Alter G, Fortune SM, Lauffenburger DA, Flynn JL, Seder RA, Maiello P, Roederer M. Darrah PA, et al. Among authors: bucsan an. Cell Host Microbe. 2023 Jun 14;31(6):962-977.e8. doi: 10.1016/j.chom.2023.05.006. Epub 2023 Jun 1. Cell Host Microbe. 2023. PMID: 37267955
Chronic Immune Activation in TB/HIV Co-infection.
Sharan R, Bucşan AN, Ganatra S, Paiardini M, Mohan M, Mehra S, Khader SA, Kaushal D. Sharan R, et al. Among authors: bucsan an. Trends Microbiol. 2020 Aug;28(8):619-632. doi: 10.1016/j.tim.2020.03.015. Epub 2020 Apr 22. Trends Microbiol. 2020. PMID: 32417227 Free PMC article. Review.
sncRNA-1 Is a Small Noncoding RNA Produced by Mycobacterium tuberculosis in Infected Cells That Positively Regulates Genes Coupled to Oleic Acid Biosynthesis.
Coskun FS, Srivastava S, Raj P, Dozmorov I, Belkaya S, Mehra S, Golden NA, Bucsan AN, Chapagain ML, Wakeland EK, Kaushal D, Gumbo T, van Oers NSC. Coskun FS, et al. Among authors: bucsan an. Front Microbiol. 2020 Jul 28;11:1631. doi: 10.3389/fmicb.2020.01631. eCollection 2020. Front Microbiol. 2020. PMID: 32849337 Free PMC article.
Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques.
Foreman TW, Bucşan AN, Mehra S, Peloquin C, Doyle LA, Russell-Lodrigue K, Gandhi NR, Altman J, Day CL, Ernst JD, Blumberg HM, Rengarajan J, Kaushal D. Foreman TW, et al. Among authors: bucsan an. Am J Respir Crit Care Med. 2020 Feb 15;201(4):469-477. doi: 10.1164/rccm.201903-0646OC. Am J Respir Crit Care Med. 2020. PMID: 31647877 Free PMC article. Retracted.
Antiretroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV coinfection model.
Ganatra SR, Bucşan AN, Alvarez X, Kumar S, Chatterjee A, Quezada M, Fish A, Singh DK, Singh B, Sharan R, Lee TH, Shanmugasundaram U, Velu V, Khader SA, Mehra S, Rengarajan J, Kaushal D. Ganatra SR, et al. Among authors: bucsan an. J Clin Invest. 2020 Oct 1;130(10):5171-5179. doi: 10.1172/JCI136502. J Clin Invest. 2020. PMID: 32544085 Free PMC article.
The immune landscape in tuberculosis reveals populations linked to disease and latency.
Esaulova E, Das S, Singh DK, Choreño-Parra JA, Swain A, Arthur L, Rangel-Moreno J, Ahmed M, Singh B, Gupta A, Fernández-López LA, de la Luz Garcia-Hernandez M, Bucsan A, Moodley C, Mehra S, García-Latorre E, Zuniga J, Atkinson J, Kaushal D, Artyomov MN, Khader SA. Esaulova E, et al. Cell Host Microbe. 2021 Feb 10;29(2):165-178.e8. doi: 10.1016/j.chom.2020.11.013. Epub 2020 Dec 18. Cell Host Microbe. 2021. PMID: 33340449 Free PMC article.
S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis.
Scott NR, Swanson RV, Al-Hammadi N, Domingo-Gonzalez R, Rangel-Moreno J, Kriel BA, Bucsan AN, Das S, Ahmed M, Mehra S, Treerat P, Cruz-Lagunas A, Jimenez-Alvarez L, Muñoz-Torrico M, Bobadilla-Lozoya K, Vogl T, Walzl G, du Plessis N, Kaushal D, Scriba TJ, Zúñiga J, Khader SA. Scott NR, et al. Among authors: bucsan an. J Clin Invest. 2020 Jun 1;130(6):3098-3112. doi: 10.1172/JCI130546. J Clin Invest. 2020. PMID: 32134742 Free PMC article.
Response to Hypoxia and the Ensuing Dysregulation of Inflammation Impacts Mycobacterium tuberculosis Pathogenicity.
Bucşan AN, Veatch A, Singh DK, Akter S, Golden NA, Kirkpatrick M, Threeton B, Moodley C, Ahmed M, Doyle LA, Russell-Lodrigue K, Norton EB, Didier PJ, Roy CJ, Abramovitch RB, Mehra S, Khader SA, Kaushal D. Bucşan AN, et al. Am J Respir Crit Care Med. 2022 Jul 1;206(1):94-104. doi: 10.1164/rccm.202112-2747OC. Am J Respir Crit Care Med. 2022. PMID: 35412961 Free PMC article.
Mechanisms of reactivation of latent tuberculosis infection due to SIV coinfection.
Bucşan AN, Chatterjee A, Singh DK, Foreman TW, Lee TH, Threeton B, Kirkpatrick MG, Ahmed M, Golden N, Alvarez X, Hoxie JA, Mehra S, Rengarajan J, Khader SA, Kaushal D. Bucşan AN, et al. J Clin Invest. 2019 Dec 2;129(12):5254-5260. doi: 10.1172/JCI125810. J Clin Invest. 2019. PMID: 31479428 Free PMC article.
26 results