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Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1.
Beach C, MacLean D, Majorova D, Melemenidis S, Nambiar DK, Kim RK, Valbuena GN, Guglietta S, Krieg C, Darvish-Damavandi M, Suwa T, Easton A, Hillson LV, McCulloch AK, McMahon RK, Pennel K, Edwards J, O'Cathail SM, Roxburgh CS, Domingo E, Moon EJ, Jiang D, Jiang Y, Zhang Q, Koong AC, Woodruff TM, Graves EE, Maughan T, Buczacki SJ, Stucki M, Le QT, Leedham SJ, Giaccia AJ, Olcina MM. Beach C, et al. Among authors: woodruff tm. J Clin Invest. 2023 Dec 1;133(23):e168277. doi: 10.1172/JCI168277. J Clin Invest. 2023. PMID: 37824211 Free PMC article.
The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization.
Wu MC, Brennan FH, Lynch JP, Mantovani S, Phipps S, Wetsel RA, Ruitenberg MJ, Taylor SM, Woodruff TM. Wu MC, et al. Among authors: woodruff tm. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9439-44. doi: 10.1073/pnas.1218815110. Epub 2013 May 21. Proc Natl Acad Sci U S A. 2013. PMID: 23696668 Free PMC article.
215 results