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Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals.
Zhang Y, Sharma S, Jonnalagadda S, Kumari S, Queen A, Esfahani SH, Archie SR, Nozohouri S, Patel D, Trippier PC, Karamyan VT, Abbruscato TJ. Zhang Y, et al. Among authors: abbruscato tj. Pharm Res. 2023 Nov;40(11):2747-2758. doi: 10.1007/s11095-023-03619-5. Epub 2023 Oct 13. Pharm Res. 2023. PMID: 37833570
Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.
Yin S, Kaluz S, Devi NS, Jabbar AA, de Noronha RG, Mun J, Zhang Z, Boreddy PR, Wang W, Wang Z, Abbruscato T, Chen Z, Olson JJ, Zhang R, Goodman MM, Nicolaou KC, Van Meir EG. Yin S, et al. Clin Cancer Res. 2012 Dec 15;18(24):6623-33. doi: 10.1158/1078-0432.CCR-12-0861. Epub 2012 Aug 24. Clin Cancer Res. 2012. PMID: 22923450 Free PMC article.
Methods for assessing drug-related anticholinergic activity.
Rudd KM, Raehl CL, Bond CA, Abbruscato TJ, Stenhouse AC. Rudd KM, et al. Among authors: abbruscato tj. Pharmacotherapy. 2005 Nov;25(11):1592-601. doi: 10.1592/phco.2005.25.11.1592. Pharmacotherapy. 2005. PMID: 16232021 Review.
Opioid receptor agonists reduce brain edema in stroke.
Yang L, Wang H, Shah K, Karamyan VT, Abbruscato TJ. Yang L, et al. Among authors: abbruscato tj. Brain Res. 2011 Apr 6;1383:307-16. doi: 10.1016/j.brainres.2011.01.083. Epub 2011 Jan 31. Brain Res. 2011. PMID: 21281614
92 results