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Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J Nat Prod. 2023 Oct 27;86(10):2283-2293. doi: 10.1021/acs.jnatprod.3c00394. Epub 2023 Oct 16.
J Nat Prod. 2023.
PMID: 37843072
Free PMC article.
Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors.
Wilson BAP, Li N, Martinez Fiesco JA, Dalilian M, Wang D, Smith EA, Wamiru A, Shah R, Goncharova EI, Beutler JA, Grkovic T, Zhang P, O'Keefe BR.
Wilson BAP, et al. Among authors: dalilian m.
ACS Pharmacol Transl Sci. 2023 Mar 21;6(4):633-650. doi: 10.1021/acsptsci.3c00010. eCollection 2023 Apr 14.
ACS Pharmacol Transl Sci. 2023.
PMID: 37082750
Free PMC article.
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Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL-B.
Khong QT, Li D, Wilson BAP, Ranguelova K, Dalilian M, Smith EA, Wamiru A, Goncharova EI, Grkovic T, Voeller D, Lipkowitz S, Schnermann MJ, O'Keefe BR, Du L.
Khong QT, et al. Among authors: dalilian m.
Org Lett. 2022 Dec 30;24(51):9468-9472. doi: 10.1021/acs.orglett.2c03922. Epub 2022 Dec 14.
Org Lett. 2022.
PMID: 36516994
Free PMC article.
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