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A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment.
De Vlieghere E, Van de Vijver K, Blondeel E, Carpentier N, Ghobeira R, Pauwels J, Riemann S, Minsart M, Fieuws C, Mestach J, Baeyens A, De Geyter N, Debbaut C, Denys H, Descamps B, Claes K, Vral A, Van Dorpe J, Gevaert K, De Geest BG, Ceelen W, Van Vlierberghe S, De Wever O. De Vlieghere E, et al. Biomater Res. 2023 Oct 18;27(1):104. doi: 10.1186/s40824-023-00441-3. Biomater Res. 2023. PMID: 37853495 Free PMC article.
Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo.
De Jaeghere E, De Vlieghere E, Van Hoorick J, Van Vlierberghe S, Wagemans G, Pieters L, Melsens E, Praet M, Van Dorpe J, Boone MN, Ghobeira R, De Geyter N, Bracke M, Vanhove C, Neyt S, Berx G, De Geest BG, Dubruel P, Declercq H, Ceelen W, De Wever O. De Jaeghere E, et al. Among authors: de vlieghere e. Biomaterials. 2018 Mar;158:95-105. doi: 10.1016/j.biomaterials.2017.12.017. Epub 2017 Dec 23. Biomaterials. 2018. PMID: 29306747
Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells.
De Vlieghere E, Gremonprez F, Verset L, Mariën L, Jones CJ, De Craene B, Berx G, Descamps B, Vanhove C, Remon JP, Ceelen W, Demetter P, Bracke M, De Geest BG, De Wever O. De Vlieghere E, et al. Among authors: de geest bg, de wever o, de craene b. Biomaterials. 2015 Jun;54:148-57. doi: 10.1016/j.biomaterials.2015.03.012. Epub 2015 Apr 2. Biomaterials. 2015. PMID: 25907048
Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation.
Tommelein J, De Vlieghere E, Verset L, Melsens E, Leenders J, Descamps B, Debucquoy A, Vanhove C, Pauwels P, Gespach CP, Vral A, De Boeck A, Haustermans K, de Tullio P, Ceelen W, Demetter P, Boterberg T, Bracke M, De Wever O. Tommelein J, et al. Among authors: de boeck a, de wever o, de tullio p, de vlieghere e. Cancer Res. 2018 Feb 1;78(3):659-670. doi: 10.1158/0008-5472.CAN-17-0524. Epub 2017 Dec 7. Cancer Res. 2018. PMID: 29217764
Data on in vivo selection of SK-OV-3 Luc ovarian cancer cells and intraperitoneal tumor formation with low inoculation numbers.
De Vlieghere E, Carlier C, Ceelen W, Bracke M, De Wever O. De Vlieghere E, et al. Among authors: de wever o. Data Brief. 2016 Jan 6;6:542-9. doi: 10.1016/j.dib.2015.12.037. eCollection 2016 Mar. Data Brief. 2016. PMID: 26904717 Free PMC article.
This data paper contains information about the in vivo model for peritoneal implants used in the paper "Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells" (De Vlieghere et al., 2015) [1]. A dou …
This data paper contains information about the in vivo model for peritoneal implants used in the paper "Tumor-environment biomimetics delay …
Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion.
Van Bockstal M, Lambein K, Van Gele M, De Vlieghere E, Limame R, Braems G, Van den Broecke R, Cocquyt V, Denys H, Bracke M, Libbrecht L, De Wever O. Van Bockstal M, et al. Among authors: de wever o, de vlieghere e. Oncoscience. 2014 Oct 15;1(10):634-48. doi: 10.18632/oncoscience.87. eCollection 2014. Oncoscience. 2014. PMID: 25593993 Free PMC article.
23 results