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A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment.
De Vlieghere E, Van de Vijver K, Blondeel E, Carpentier N, Ghobeira R, Pauwels J, Riemann S, Minsart M, Fieuws C, Mestach J, Baeyens A, De Geyter N, Debbaut C, Denys H, Descamps B, Claes K, Vral A, Van Dorpe J, Gevaert K, De Geest BG, Ceelen W, Van Vlierberghe S, De Wever O. De Vlieghere E, et al. Among authors: descamps b. Biomater Res. 2023 Oct 18;27(1):104. doi: 10.1186/s40824-023-00441-3. Biomater Res. 2023. PMID: 37853495 Free PMC article.
Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells.
De Vlieghere E, Gremonprez F, Verset L, Mariën L, Jones CJ, De Craene B, Berx G, Descamps B, Vanhove C, Remon JP, Ceelen W, Demetter P, Bracke M, De Geest BG, De Wever O. De Vlieghere E, et al. Among authors: descamps b. Biomaterials. 2015 Jun;54:148-57. doi: 10.1016/j.biomaterials.2015.03.012. Epub 2015 Apr 2. Biomaterials. 2015. PMID: 25907048
Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation.
Tommelein J, De Vlieghere E, Verset L, Melsens E, Leenders J, Descamps B, Debucquoy A, Vanhove C, Pauwels P, Gespach CP, Vral A, De Boeck A, Haustermans K, de Tullio P, Ceelen W, Demetter P, Boterberg T, Bracke M, De Wever O. Tommelein J, et al. Among authors: descamps b. Cancer Res. 2018 Feb 1;78(3):659-670. doi: 10.1158/0008-5472.CAN-17-0524. Epub 2017 Dec 7. Cancer Res. 2018. PMID: 29217764
129 results