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Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice.
Beretta M, Dai Y, Olzomer EM, Vancuylenburg CS, Santiago-Rivera JA, Philp AM, Hargett SR, Li K, Shah DP, Chen SY, Alexopoulos SJ, Li C, Harris TE, Lee B, Wathier M, Cermak JM, Tucker SP, Turner N, Bayliss DA, Philp A, Byrne FL, Santos WL, Hoehn KL. Beretta M, et al. Among authors: li c, li k. Diabetes. 2024 Mar 1;73(3):374-384. doi: 10.2337/db23-0233. Diabetes. 2024. PMID: 37870907 Free PMC article.
PHYSIOLOGY. Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons.
Kumar NN, Velic A, Soliz J, Shi Y, Li K, Wang S, Weaver JL, Sen J, Abbott SB, Lazarenko RM, Ludwig MG, Perez-Reyes E, Mohebbi N, Bettoni C, Gassmann M, Suply T, Seuwen K, Guyenet PG, Wagner CA, Bayliss DA. Kumar NN, et al. Among authors: li k. Science. 2015 Jun 12;348(6240):1255-60. doi: 10.1126/science.aaa0922. Epub 2015 Jun 11. Science. 2015. PMID: 26068853 Free PMC article.
A brainstem peptide system activated at birth protects postnatal breathing.
Shi Y, Stornetta DS, Reklow RJ, Sahu A, Wabara Y, Nguyen A, Li K, Zhang Y, Perez-Reyes E, Ross RA, Lowell BB, Stornetta RL, Funk GD, Guyenet PG, Bayliss DA. Shi Y, et al. Among authors: li k. Nature. 2021 Jan;589(7842):426-430. doi: 10.1038/s41586-020-2991-4. Epub 2020 Dec 2. Nature. 2021. PMID: 33268898 Free PMC article.
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