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SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Choy C, Chen J, Li J, Gallagher DT, Lu J, Wu D, Zou A, Hemani H, Baptiste BA, Wichmann E, Yang Q, Ciffelo J, Yin R, McKelvy J, Melvin D, Wallace T, Dunn C, Nguyen C, Chia CW, Fan J, Ruffolo J, Zukley L, Shi G, Amano T, An Y, Meirelles O, Wu WW, Chou CK, Shen RF, Willis RA, Ko MSH, Liu YT, De S, Pierce BG, Ferrucci L, Egan J, Mariuzza R, Weng NP. Choy C, et al. Among authors: egan j. Nat Commun. 2023 Oct 23;14(1):6725. doi: 10.1038/s41467-023-42430-z. Nat Commun. 2023. PMID: 37872153 Free PMC article.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: egan jm. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528512. doi: 10.1101/2023.02.14.528512. bioRxiv. 2023. PMID: 36824822 Free PMC article. Updated. Preprint.
Longitudinal phenotypic aging metrics in the Baltimore Longitudinal Study of Aging.
Kuo PL, Schrack JA, Levine ME, Shardell MD, Simonsick EM, Chia CW, Moore AZ, Tanaka T, An Y, Karikkineth A, AlGhatrif M, Elango P, Zukley LM, Egan JM, de Cabo R, Resnick SM, Ferrucci L. Kuo PL, et al. Nat Aging. 2022 Jul;2(7):635-643. doi: 10.1038/s43587-022-00243-7. Epub 2022 Jul 18. Nat Aging. 2022. PMID: 36910594 Free PMC article.
Endocrinology of Taste with Aging.
Chia CW, Yeager SM, Egan JM. Chia CW, et al. Endocrinol Metab Clin North Am. 2023 Jun;52(2):295-315. doi: 10.1016/j.ecl.2022.10.002. Epub 2023 Feb 16. Endocrinol Metab Clin North Am. 2023. PMID: 36948781 Review.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: egan jm. Mol Cell. 2023 May 18;83(10):1659-1676.e11. doi: 10.1016/j.molcel.2023.04.005. Epub 2023 Apr 27. Mol Cell. 2023. PMID: 37116496 Free PMC article.
Cross-sectional analysis of healthy individuals across decades: Aging signatures across multiple physiological compartments.
Moaddel R, Ubaida-Mohien C, Tanaka T, Tian Q, Candia J, Moore AZ, Lovett J, Fantoni G, Shehadeh N, Turek L, Collingham V, Kaileh M, Chia CW, Sen R, Egan JM, Ferrucci L. Moaddel R, et al. Among authors: egan jm. Aging Cell. 2024 Jan;23(1):e13902. doi: 10.1111/acel.13902. Epub 2023 Jun 23. Aging Cell. 2024. PMID: 37350292 Free PMC article.
Long-Term Dysfunction of Taste Papillae in SARS-CoV-2.
Yao Q, Doyle ME, Liu QR, Appleton A, O'Connell JF, Weng NP, Egan JM. Yao Q, et al. NEJM Evid. 2023 Sep;2(9):10.1056/evidoa2300046. doi: 10.1056/evidoa2300046. Epub 2023 Jul 20. NEJM Evid. 2023. PMID: 38145006 Free PMC article.
Cerebrospinal fluid exploratory proteomics and ketamine metabolite pharmacokinetics in human volunteers after ketamine infusion.
Moaddel R, Farmer CA, Yavi M, Kadriu B, Zhu M, Fan J, Chen Q, Lehrmann E, Fantoni G, De S, Mazucanti CH, Acevedo-Diaz EE, Yuan P, Gould TD, Park LT, Egan JM, Ferrucci L, Zarate CA Jr. Moaddel R, et al. Among authors: egan jm. iScience. 2023 Nov 23;26(12):108527. doi: 10.1016/j.isci.2023.108527. eCollection 2023 Dec 15. iScience. 2023. PMID: 38162029 Free PMC article.
1,336 results