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SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Choy C, Chen J, Li J, Gallagher DT, Lu J, Wu D, Zou A, Hemani H, Baptiste BA, Wichmann E, Yang Q, Ciffelo J, Yin R, McKelvy J, Melvin D, Wallace T, Dunn C, Nguyen C, Chia CW, Fan J, Ruffolo J, Zukley L, Shi G, Amano T, An Y, Meirelles O, Wu WW, Chou CK, Shen RF, Willis RA, Ko MSH, Liu YT, De S, Pierce BG, Ferrucci L, Egan J, Mariuzza R, Weng NP. Choy C, et al. Among authors: fan j. Nat Commun. 2023 Oct 23;14(1):6725. doi: 10.1038/s41467-023-42430-z. Nat Commun. 2023. PMID: 37872153 Free PMC article.
A BDNF-TrkB autocrine loop enhances senescent cell viability.
Anerillas C, Herman AB, Munk R, Garrido A, Lam KG, Payea MJ, Rossi M, Tsitsipatis D, Martindale JL, Piao Y, Mazan-Mamczarz K, Fan J, Cui CY, De S, Abdelmohsen K, de Cabo R, Gorospe M. Anerillas C, et al. Among authors: fan j. Nat Commun. 2022 Oct 20;13(1):6228. doi: 10.1038/s41467-022-33709-8. Nat Commun. 2022. PMID: 36266274 Free PMC article.
Author Correction: A BDNF-TrkB autocrine loop enhances senescent cell viability.
Anerillas C, Herman AB, Munk R, Garrido A, Lam KG, Payea MJ, Rossi M, Tsitsipatis D, Martindale JL, Piao Y, Mazan-Mamczarz K, Fan J, Cui CY, De S, Abdelmohsen K, de Cabo R, Gorospe M. Anerillas C, et al. Among authors: fan j. Nat Commun. 2022 Dec 7;13(1):7540. doi: 10.1038/s41467-022-35154-z. Nat Commun. 2022. PMID: 36477003 Free PMC article. No abstract available.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: fan j. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528512. doi: 10.1101/2023.02.14.528512. bioRxiv. 2023. PMID: 36824822 Free PMC article. Updated. Preprint.
Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging.
Occean JR, Yang N, Sun Y, Dawkins MS, Munk R, Belair C, Dar S, Anerillas C, Wang L, Shi C, Dunn C, Bernier M, Price NL, Kim JS, Cui CY, Fan J, Bhattacharyya M, De S, Maragkakis M, deCabo R, Sidoli S, Sen P. Occean JR, et al. Among authors: fan j. bioRxiv [Preprint]. 2023 Feb 15:2023.02.15.528714. doi: 10.1101/2023.02.15.528714. bioRxiv. 2023. PMID: 36824863 Free PMC article. Preprint.
Pleiotropic effects of BAFF on the senescence-associated secretome and growth arrest.
Rossi M, Anerillas C, Idda ML, Munk R, Shin CH, Donega S, Tsitsipatis D, Herman AB, Martindale JL, Yang X, Piao Y, Mazan-Mamczarz K, Fan J, Ferrucci L, Johnson PF, De S, Abdelmohsen K, Gorospe M. Rossi M, et al. Among authors: fan j. Elife. 2023 Apr 21;12:e84238. doi: 10.7554/eLife.84238. Elife. 2023. PMID: 37083495 Free PMC article.
DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice.
Herman AB, Tsitsipatis D, Anerillas C, Mazan-Mamczarz K, Carr AE, Gregg JM, Wang M, Zhang J, Michel M, Henry-Smith CA, Harris SC, Munk R, Martindale JL, Piao Y, Fan J, Mattison JA, De S, Abdelmohsen K, Maul RW, Tanaka T, Moore AZ, DeMouth ME, Sidoli S, Ferrucci L, Liu Y, de Cabo R, Lakatta EG, Gorospe M. Herman AB, et al. Among authors: fan j. J Clin Invest. 2023 Jun 15;133(12):e165933. doi: 10.1172/JCI165933. J Clin Invest. 2023. PMID: 37097759 Free PMC article.
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