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SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Choy C, Chen J, Li J, Gallagher DT, Lu J, Wu D, Zou A, Hemani H, Baptiste BA, Wichmann E, Yang Q, Ciffelo J, Yin R, McKelvy J, Melvin D, Wallace T, Dunn C, Nguyen C, Chia CW, Fan J, Ruffolo J, Zukley L, Shi G, Amano T, An Y, Meirelles O, Wu WW, Chou CK, Shen RF, Willis RA, Ko MSH, Liu YT, De S, Pierce BG, Ferrucci L, Egan J, Mariuzza R, Weng NP. Choy C, et al. Among authors: zukley l. Nat Commun. 2023 Oct 23;14(1):6725. doi: 10.1038/s41467-023-42430-z. Nat Commun. 2023. PMID: 37872153 Free PMC article.
Heterogeneity and transcriptome changes of human CD8+ T cells across nine decades of life.
Lu J, Ahmad R, Nguyen T, Cifello J, Hemani H, Li J, Chen J, Li S, Wang J, Achour A, Chen J, Colie M, Lustig A, Dunn C, Zukley L, Chia CW, Burd I, Zhu J, Ferrucci L, Weng NP. Lu J, et al. Among authors: zukley l. Nat Commun. 2022 Sep 1;13(1):5128. doi: 10.1038/s41467-022-32869-x. Nat Commun. 2022. PMID: 36050300 Free PMC article.
Skeletal muscle transcriptome in healthy aging.
Tumasian RA 3rd, Harish A, Kundu G, Yang JH, Ubaida-Mohien C, Gonzalez-Freire M, Kaileh M, Zukley LM, Chia CW, Lyashkov A, Wood WH 3rd, Piao Y, Coletta C, Ding J, Gorospe M, Sen R, De S, Ferrucci L. Tumasian RA 3rd, et al. Among authors: zukley lm. Nat Commun. 2021 Apr 1;12(1):2014. doi: 10.1038/s41467-021-22168-2. Nat Commun. 2021. PMID: 33795677 Free PMC article.
Longitudinal phenotypic aging metrics in the Baltimore Longitudinal Study of Aging.
Kuo PL, Schrack JA, Levine ME, Shardell MD, Simonsick EM, Chia CW, Moore AZ, Tanaka T, An Y, Karikkineth A, AlGhatrif M, Elango P, Zukley LM, Egan JM, de Cabo R, Resnick SM, Ferrucci L. Kuo PL, et al. Among authors: zukley lm. Nat Aging. 2022 Jul;2(7):635-643. doi: 10.1038/s43587-022-00243-7. Epub 2022 Jul 18. Nat Aging. 2022. PMID: 36910594 Free PMC article.
Epigenetic signature of human immune aging in the GESTALT study.
Roy R, Kuo PL, Candia J, Sarantopoulou D, Ubaida-Mohien C, Hernandez D, Kaileh M, Arepalli S, Singh A, Bektas A, Kim J, Moore AZ, Tanaka T, McKelvey J, Zukley L, Nguyen C, Wallace T, Dunn C, Wood W, Piao Y, Coletta C, De S, Sen J, Weng NP, Sen R, Ferrucci L. Roy R, et al. Among authors: zukley l. Elife. 2023 Aug 17;12:e86136. doi: 10.7554/eLife.86136. Elife. 2023. PMID: 37589453 Free PMC article.
Age-associated expression of p21and p53 during human wound healing.
Chia CW, Sherman-Baust CA, Larson SA, Pandey R, Withers R, Karikkineth AC, Zukley LM, Campisi J, Egan JM, Sen R, Ferrucci L. Chia CW, et al. Among authors: zukley lm. Aging Cell. 2021 May;20(5):e13354. doi: 10.1111/acel.13354. Epub 2021 Apr 9. Aging Cell. 2021. PMID: 33835683 Free PMC article.
DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.
Roy R, Ramamoorthy S, Shapiro BD, Kaileh M, Hernandez D, Sarantopoulou D, Arepalli S, Boller S, Singh A, Bektas A, Kim J, Moore AZ, Tanaka T, McKelvey J, Zukley L, Nguyen C, Wallace T, Dunn C, Wersto R, Wood W, Piao Y, Becker KG, Coletta C, De S, Sen JM, Battle A, Weng NP, Grosschedl R, Ferrucci L, Sen R. Roy R, et al. Among authors: zukley l. Immunity. 2021 Nov 9;54(11):2465-2480.e5. doi: 10.1016/j.immuni.2021.10.001. Epub 2021 Oct 26. Immunity. 2021. PMID: 34706222 Free PMC article.
Telomere Length as an Indicator of the Robustness of B- and T-Cell Response to Influenza in Older Adults.
Najarro K, Nguyen H, Chen G, Xu M, Alcorta S, Yao X, Zukley L, Metter EJ, Truong T, Lin Y, Li H, Oelke M, Xu X, Ling SM, Longo DL, Schneck J, Leng S, Ferrucci L, Weng NP. Najarro K, et al. Among authors: zukley l. J Infect Dis. 2015 Oct 15;212(8):1261-9. doi: 10.1093/infdis/jiv202. Epub 2015 Mar 31. J Infect Dis. 2015. PMID: 25828247 Free PMC article.
29 results