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De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression.
Tangudu NK, Buj R, Wang H, Wang J, Cole AR, Uboveja A, Fang R, Amalric A, Sajjakulnukit P, Lyons MA, Cooper K, Hempel N, Snyder NW, Lyssiotis CA, Chandran UR, Aird KM. Tangudu NK, et al. Among authors: hempel n. bioRxiv [Preprint]. 2023 Sep 23:2023.07.15.549149. doi: 10.1101/2023.07.15.549149. bioRxiv. 2023. PMID: 37503050 Free PMC article. Updated. Preprint.
A multiple-oscillator mechanism underlies antigen-induced Ca2+ oscillations in Jurkat T-cells.
Benson JC, Romito O, Abdelnaby AE, Xin P, Pathak T, Weir SE, Kirk V, Castaneda F, Yoast RE, Emrich SM, Tang PW, Yule DI, Hempel N, Potier-Cartereau M, Sneyd J, Trebak M. Benson JC, et al. Among authors: hempel n. J Biol Chem. 2023 Nov;299(11):105310. doi: 10.1016/j.jbc.2023.105310. Epub 2023 Sep 29. J Biol Chem. 2023. PMID: 37778728 Free PMC article.
Alternative splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and tumor progression in ovarian cancer.
Javed Z, Shin DH, Pan W, White SR, Kim YS, Elhaw AT, Kamlapurkar S, Cheng YY, Benson JC, Abdelnaby AE, Phaëton R, Wang HG, Yang S, Sullivan MLG, St Croix CM, Watkins SC, Mullett SJ, Gelhaus SL, Lee N, Coffman LG, Aird KM, Trebak M, Mythreye K, Walter V, Hempel N. Javed Z, et al. Among authors: hempel n. bioRxiv [Preprint]. 2024 Jan 24:2023.09.20.558501. doi: 10.1101/2023.09.20.558501. bioRxiv. 2024. PMID: 37790404 Free PMC article. Preprint.
Targeted rescue of synaptic plasticity improves cognitive decline in sepsis-associated encephalopathy.
Grünewald B, Wickel J, Hahn N, Rahmati V, Rupp H, Chung HY, Haselmann H, Strauss AS, Schmidl L, Hempel N, Grünewald L, Urbach A, Bauer M, Toyka KV, Blaess M, Claus RA, König R, Geis C. Grünewald B, et al. Among authors: hempel n. Mol Ther. 2024 May 23:S1525-0016(24)00301-0. doi: 10.1016/j.ymthe.2024.05.001. Online ahead of print. Mol Ther. 2024. PMID: 38788710 Free article.
90 results