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ASCT2 is the primary serine transporter in cancer cells.
Conger KO, Chidley C, Ozgurses ME, Zhao H, Kim Y, Semina SE, Burns P, Rawat V, Sheldon R, Ben-Sahra I, Frasor J, Sorger PK, DeNicola GM, Coloff JL. Conger KO, et al. Among authors: coloff jl. bioRxiv [Preprint]. 2023 Oct 11:2023.10.09.561530. doi: 10.1101/2023.10.09.561530. bioRxiv. 2023. PMID: 37873453 Free PMC article. Preprint.
Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.
Rawat V, DeLear P, Prashanth P, Ozgurses ME, Tebeje A, Burns PA, Conger KO, Solís C, Hasnain Y, Novikova A, Endress JE, González-Sánchez P, Dong W, Stephanopoulos G, DeNicola GM, Harris IS, Sept D, Mason FM, Coloff JL. Rawat V, et al. Among authors: coloff jl. bioRxiv [Preprint]. 2023 Jul 28:2023.07.26.550731. doi: 10.1101/2023.07.26.550731. bioRxiv. 2023. PMID: 37546939 Free PMC article. Preprint.
Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.
Rawat V, DeLear P, Prashanth P, Ozgurses ME, Tebeje A, Burns PA, Conger KO, Solís C, Hasnain Y, Novikova A, Endress JE, González-Sánchez P, Dong W, Stephanopoulos G, DeNicola GM, Harris I, Sept D, Mason FM, Coloff JL. Rawat V, et al. Among authors: coloff jl. JCI Insight. 2024 May 30:e174329. doi: 10.1172/jci.insight.174329. Online ahead of print. JCI Insight. 2024. PMID: 38815134 Free article.
Correction to: SOX2 mediates metabolic reprogramming of prostate cancer cells.
de Wet L, Williams A, Gillard M, Kregel S, Lamperis S, Gutgesell LC, Vellky JE, Brown R, Conger K, Paner GP, Wang H, Platz EA, De Marzo AM, Mu P, Coloff JL, Szmulewitz RZ, Vander Griend DJ. de Wet L, et al. Among authors: coloff jl. Oncogene. 2022 Feb;41(8):1234. doi: 10.1038/s41388-022-02228-7. Oncogene. 2022. PMID: 35145235 No abstract available.
SOX2 mediates metabolic reprogramming of prostate cancer cells.
de Wet L, Williams A, Gillard M, Kregel S, Lamperis S, Gutgesell LC, Vellky JE, Brown R, Conger K, Paner GP, Wang H, Platz EA, De Marzo AM, Mu P, Coloff JL, Szmulewitz RZ, Vander Griend DJ. de Wet L, et al. Among authors: coloff jl. Oncogene. 2022 Feb;41(8):1190-1202. doi: 10.1038/s41388-021-02157-x. Epub 2022 Jan 24. Oncogene. 2022. PMID: 35067686 Free PMC article.
Differential substrate use in EGF- and oncogenic KRAS-stimulated human mammary epithelial cells.
Keibler MA, Dong W, Korthauer KD, Hosios AM, Moon SJ, Sullivan LB, Liu N, Abbott KL, Arevalo OD, Ho K, Lee J, Phanse AS, Kelleher JK, Iliopoulos O, Coloff JL, Vander Heiden MG, Stephanopoulos G. Keibler MA, et al. Among authors: coloff jl. FEBS J. 2021 Oct;288(19):5629-5649. doi: 10.1111/febs.15858. Epub 2021 May 13. FEBS J. 2021. PMID: 33811729 Free PMC article.
PHGDH supports liver ceramide synthesis and sustains lipid homeostasis.
Kang YP, Falzone A, Liu M, González-Sánchez P, Choi BH, Coloff JL, Saller JJ, Karreth FA, DeNicola GM. Kang YP, et al. Among authors: coloff jl. Cancer Metab. 2020 Jun 15;8:6. doi: 10.1186/s40170-020-00212-x. eCollection 2020. Cancer Metab. 2020. PMID: 32549981 Free PMC article.
Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.
Harris IS, Endress JE, Coloff JL, Selfors LM, McBrayer SK, Rosenbluth JM, Takahashi N, Dhakal S, Koduri V, Oser MG, Schauer NJ, Doherty LM, Hong AL, Kang YP, Younger ST, Doench JG, Hahn WC, Buhrlage SJ, DeNicola GM, Kaelin WG Jr, Brugge JS. Harris IS, et al. Among authors: coloff jl. Cell Metab. 2019 May 7;29(5):1166-1181.e6. doi: 10.1016/j.cmet.2019.01.020. Epub 2019 Feb 21. Cell Metab. 2019. PMID: 30799286 Free PMC article.
41 results