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Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion.
Chauhan NR, Kundu S, Bal R, Chattopadhyay D, Sahu R, Mehto S, Yadav R, Krishna S, Jena KK, Satapathy S, Pv A, Murmu KC, Singh B, Patnaik S, Jena S, Harshan KH, Syed GH, Idris MM, Prasad P, Chauhan S. Chauhan NR, et al. Among authors: mehto s. Cell Rep. 2023 Nov 28;42(11):113275. doi: 10.1016/j.celrep.2023.113275. Epub 2023 Oct 23. Cell Rep. 2023. PMID: 37874678 Free article.
Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses.
Nath P, Chauhan NR, Jena KK, Datey A, Kumar ND, Mehto S, De S, Nayak TK, Priyadarsini S, Rout K, Bal R, Murmu KC, Kalia M, Patnaik S, Prasad P, Reggiori F, Chattopadhyay S, Chauhan S. Nath P, et al. Among authors: mehto s. EMBO Rep. 2021 Nov 4;22(11):e52948. doi: 10.15252/embr.202152948. Epub 2021 Sep 1. EMBO Rep. 2021. PMID: 34467632 Free PMC article.
IRGM links autoimmunity to autophagy.
Nath P, Jena KK, Mehto S, Chauhan NR, Sahu R, Dhar K, Srinivas K, Chauhan S, Chauhan S. Nath P, et al. Among authors: mehto s. Autophagy. 2021 Feb;17(2):578-580. doi: 10.1080/15548627.2020.1810920. Epub 2020 Aug 23. Autophagy. 2021. PMID: 32813580 Free PMC article. Review.
RIPosomes are targets of IRGM-SQSTM1-dependent autophagy.
Mehto S, Kundu S, Chauhan S, Chauhan S. Mehto S, et al. Autophagy. 2023 Mar;19(3):1045-1047. doi: 10.1080/15548627.2023.2166724. Epub 2023 Jan 18. Autophagy. 2023. PMID: 36628446 Free PMC article.
20 results