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Structural surfaceomics reveals an AML-specific conformation of integrin β2 as a CAR T cellular therapy target.
Mandal K, Wicaksono G, Yu C, Adams JJ, Hoopmann MR, Temple WC, Izgutdina A, Escobar BP, Gorelik M, Ihling CH, Nix MA, Naik A, Xie WH, Hübner J, Rollins LA, Reid SM, Ramos E, Kasap C, Steri V, Serrano JAC, Salangsang F, Phojanakong P, McMillan M, Gavallos V, Leavitt AD, Logan AC, Rooney CM, Eyquem J, Sinz A, Huang BJ, Stieglitz E, Smith CC, Moritz RL, Sidhu SS, Huang L, Wiita AP. Mandal K, et al. Among authors: sidhu ss. Nat Cancer. 2023 Nov;4(11):1592-1609. doi: 10.1038/s43018-023-00652-6. Epub 2023 Oct 30. Nat Cancer. 2023. PMID: 37904046 Free PMC article.
Synthetic antibody technologies.
Adams JJ, Sidhu SS. Adams JJ, et al. Among authors: sidhu ss. Curr Opin Struct Biol. 2014 Feb;24:1-9. doi: 10.1016/j.sbi.2013.11.003. Epub 2013 Dec 4. Curr Opin Struct Biol. 2014. PMID: 24721448 Review.
Blockade of TGF-β signaling with novel synthetic antibodies limits immune exclusion and improves chemotherapy response in metastatic ovarian cancer models.
Newsted D, Banerjee S, Watt K, Nersesian S, Truesdell P, Blazer LL, Cardarelli L, Adams JJ, Sidhu SS, Craig AW. Newsted D, et al. Among authors: sidhu ss. Oncoimmunology. 2018 Nov 20;8(2):e1539613. doi: 10.1080/2162402X.2018.1539613. eCollection 2019. Oncoimmunology. 2018. PMID: 30713798 Free PMC article.
462 results