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The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency.
Sperber HS, Raymond KA, Bouzidi MS, Ma T, Valdebenito S, Eugenin EA, Roan NR, Deeks SG, Winning S, Fandrey J, Schwarzer R, Pillai SK. Sperber HS, et al. Among authors: roan nr. Cell Rep. 2023 Nov 28;42(11):113285. doi: 10.1016/j.celrep.2023.113285. Epub 2023 Oct 31. Cell Rep. 2023. PMID: 37910505 Free PMC article.
Mild HIV-specific selective forces overlaying natural CD4+ T cell dynamics explain the clonality and decay dynamics of HIV reservoir cells.
Reeves DB, Rigau DN, Romero A, Zhang H, Simonetti FR, Varriale J, Hoh R, Zhang L, Smith KN, Montaner LJ, Rubin LH, Gange SJ, Roan NR, Tien PC, Margolick JB, Peluso MJ, Deeks SG, Schiffer JT, Siliciano JD, Siliciano RF, Antar AAR. Reeves DB, et al. Among authors: roan nr. medRxiv [Preprint]. 2024 Feb 15:2024.02.13.24302704. doi: 10.1101/2024.02.13.24302704. medRxiv. 2024. PMID: 38405967 Free PMC article. Preprint.
Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection.
Thaweethai T, Jolley SE, Karlson EW, Levitan EB, Levy B, McComsey GA, McCorkell L, Nadkarni GN, Parthasarathy S, Singh U, Walker TA, Selvaggi CA, Shinnick DJ, Schulte CCM, Atchley-Challenner R, Alba GA, Alicic R, Altman N, Anglin K, Argueta U, Ashktorab H, Baslet G, Bassett IV, Bateman L, Bedi B, Bhattacharyya S, Bind MA, Blomkalns AL, Bonilla H, Bush PA, Castro M, Chan J, Charney AW, Chen P, Chibnik LB, Chu HY, Clifton RG, Costantine MM, Cribbs SK, Davila Nieves SI, Deeks SG, Duven A, Emery IF, Erdmann N, Erlandson KM, Ernst KC, Farah-Abraham R, Farner CE, Feuerriegel EM, Fleurimont J, Fonseca V, Franko N, Gainer V, Gander JC, Gardner EM, Geng LN, Gibson KS, Go M, Goldman JD, Grebe H, Greenway FL, Habli M, Hafner J, Han JE, Hanson KA, Heath J, Hernandez C, Hess R, Hodder SL, Hoffman MK, Hoover SE, Huang B, Hughes BL, Jagannathan P, John J, Jordan MR, Katz SD, Kaufman ES, Kelly JD, Kelly SW, Kemp MM, Kirwan JP, Klein JD, Knox KS, Krishnan JA, Kumar A, Laiyemo AO, Lambert AA, Lanca M, Lee-Iannotti JK, Logarbo BP, Longo MT, Luciano CA, Lutrick K, Maley JH, Marathe JG, Marconi V, Marshall GD, Martin CF, Matusov Y, Mehari A, Mendez-Figueroa H, Mermelstein R, Metz TD, Morse R, Mosier J… See abstract for full author list ➔ Thaweethai T, et al. JAMA. 2023 Jun 13;329(22):1934-1946. doi: 10.1001/jama.2023.8823. JAMA. 2023. PMID: 37278994 Free PMC article.
Systems analysis of innate and adaptive immunity in Long COVID.
Peluso MJ, Abdel-Mohsen M, Henrich TJ, Roan NR. Peluso MJ, et al. Among authors: roan nr. Semin Immunol. 2024 Mar;72:101873. doi: 10.1016/j.smim.2024.101873. Epub 2024 Mar 8. Semin Immunol. 2024. PMID: 38460395 Review.
Immunoglobulin G N-glycan markers of accelerated biological aging during chronic HIV infection.
Giron LB, Liu Q, Adeniji OS, Yin X, Kannan T, Ding J, Lu DY, Langan S, Zhang J, Azevedo JLLC, Li SH, Shalygin S, Azadi P, Hanna DB, Ofotokun I, Lazar J, Fischl MA, Haberlen S, Macatangay B, Adimora AA, Jamieson BD, Rinaldo C, Merenstein D, Roan NR, Kutsch O, Gange S, Wolinsky SM, Witt MD, Post WS, Kossenkov A, Landay AL, Frank I, Tien PC, Gross R, Brown TT, Abdel-Mohsen M. Giron LB, et al. Among authors: roan nr. Nat Commun. 2024 Apr 10;15(1):3035. doi: 10.1038/s41467-024-47279-4. Nat Commun. 2024. PMID: 38600088 Free PMC article.
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2.
Yin K, Peluso MJ, Luo X, Thomas R, Shin MG, Neidleman J, Andrew A, Young KC, Ma T, Hoh R, Anglin K, Huang B, Argueta U, Lopez M, Valdivieso D, Asare K, Deveau TM, Munter SE, Ibrahim R, Ständker L, Lu S, Goldberg SA, Lee SA, Lynch KL, Kelly JD, Martin JN, Münch J, Deeks SG, Henrich TJ, Roan NR. Yin K, et al. Among authors: roan nr. Nat Immunol. 2024 Feb;25(2):218-225. doi: 10.1038/s41590-023-01724-6. Epub 2024 Jan 11. Nat Immunol. 2024. PMID: 38212464 Free PMC article.
HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing.
Lyons DE, Kumar P, Roan NR, Defechereux PA, Feschotte C, Lange UC, Murthy N, Sameshima P, Verdin E, Ake JA, Parsons MS, Nath A, Gianella S, Smith DM, Kallas EG, Villa TJ, Strange R, Mwesigwa B, Furler O'Brien RL, Nixon DF, Ndhlovu LC, Valente ST, Ott M. Lyons DE, et al. Among authors: roan nr. Viruses. 2023 Oct 28;15(11):2171. doi: 10.3390/v15112171. Viruses. 2023. PMID: 38005849 Free PMC article.
Plasma Glycomic Markers of Accelerated Biological Aging During Chronic HIV Infection.
Giron LB, Liu Q, Adeniji OS, Yin X, Kannan T, Ding J, Lu DY, Langan S, Zhang J, Azevedo JLLC, Li SH, Shalygin S, Azadi P, Hanna DB, Ofotokun I, Lazar J, Fischl MA, Haberlen S, Macatangay B, Adimora AA, Jamieson BD, Rinaldo C, Merenstein D, Roan NR, Kutsch O, Gange S, Wolinsky S, Witt M, Post WS, Kossenkov A, Landay A, Frank I, Tien PC, Gross R, Brown TT, Abdel-Mohsen M. Giron LB, et al. Among authors: roan nr. bioRxiv [Preprint]. 2023 Dec 31:2023.08.09.551369. doi: 10.1101/2023.08.09.551369. bioRxiv. 2023. PMID: 37609144 Free PMC article. Updated. Preprint.
Post-acute immunological and behavioral sequelae in mice after Omicron infection.
Ma T, Suryawanshi RK, Miller SR, Ly KK, Thomas R, Elphick N, Yin K, Luo X, Kaliss N, Chen IP, Montano M, Sreekumar B, Standker L, Münch J, Heath Damron F, Palop JJ, Ott M, Roan NR. Ma T, et al. Among authors: roan nr. bioRxiv [Preprint]. 2023 Oct 4:2023.06.05.543758. doi: 10.1101/2023.06.05.543758. bioRxiv. 2023. PMID: 37333294 Free PMC article. Preprint.
96 results