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Loss of ZNF148 enhances insulin secretion in human pancreatic β cells.
de Klerk E, Xiao Y, Emfinger CH, Keller MP, Berrios DI, Loconte V, Ekman AA, White KL, Cardone RL, Kibbey RG, Attie AD, Hebrok M. de Klerk E, et al. Among authors: emfinger ch. JCI Insight. 2023 Jun 8;8(11):e157572. doi: 10.1172/jci.insight.157572. JCI Insight. 2023. PMID: 37288664 Free PMC article.
β Cell-specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses.
Emfinger CH, de Klerk E, Schueler KL, Rabaglia ME, Stapleton DS, Simonett SP, Mitok KA, Wang Z, Liu X, Paulo JA, Yu Q, Cardone RL, Foster HR, Lewandowski SL, Perales JC, Kendziorski CM, Gygi SP, Kibbey RG, Keller MP, Hebrok M, Merrins MJ, Attie AD. Emfinger CH, et al. JCI Insight. 2022 May 23;7(10):e154198. doi: 10.1172/jci.insight.154198. JCI Insight. 2022. PMID: 35603790 Free PMC article.
ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9.
Smeland MF, McClenaghan C, Roessler HI, Savelberg S, Hansen GÅM, Hjellnes H, Arntzen KA, Müller KI, Dybesland AR, Harter T, Sala-Rabanal M, Emfinger CH, Huang Y, Singareddy SS, Gunn J, Wozniak DF, Kovacs A, Massink M, Tessadori F, Kamel SM, Bakkers J, Remedi MS, Van Ghelue M, Nichols CG, van Haaften G. Smeland MF, et al. Among authors: emfinger ch. Nat Commun. 2019 Oct 1;10(1):4457. doi: 10.1038/s41467-019-12428-7. Nat Commun. 2019. PMID: 31575858 Free PMC article.
Gene loci associated with insulin secretion in islets from non-diabetic mice.
Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Vincent M, Mitok KA, Wang Z, Ishimura T, Simonett SP, Emfinger CH, Das R, Beck T, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD. Keller MP, et al. Among authors: emfinger ch. J Clin Invest. 2019 Jul 25;129(10):4419-4432. doi: 10.1172/JCI129143. J Clin Invest. 2019. PMID: 31343992 Free PMC article.
Beta-cell excitability and excitability-driven diabetes in adult Zebrafish islets.
Emfinger CH, Lőrincz R, Wang Y, York NW, Singareddy SS, Ikle JM, Tryon RC, McClenaghan C, Shyr ZA, Huang Y, Reissaus CA, Meyer D, Piston DW, Hyrc K, Remedi MS, Nichols CG. Emfinger CH, et al. Physiol Rep. 2019 Jun;7(11):e14101. doi: 10.14814/phy2.14101. Physiol Rep. 2019. PMID: 31161721 Free PMC article.
15 results