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Endoplasmic reticulum-associated degradation is required for nephrin maturation and kidney glomerular filtration function.
Yoshida S, Wei X, Zhang G, O'Connor CL, Torres M, Zhou Z, Lin L, Menon R, Xu X, Zheng W, Xiong Y, Otto E, Tang CA, Hua R, Verma R, Mori H, Zhang Y, Hu CA, Liu M, Garg P, Hodgin JB, Sun S, Bitzer M, Qi L. Yoshida S, et al. J Clin Invest. 2021 Apr 1;131(7):e143988. doi: 10.1172/JCI143988. J Clin Invest. 2021. PMID: 33591954 Free PMC article.
Glomerular Aging and Focal Global Glomerulosclerosis: A Podometric Perspective.
Hodgin JB, Bitzer M, Wickman L, Afshinnia F, Wang SQ, O'Connor C, Yang Y, Meadowbrooke C, Chowdhury M, Kikuchi M, Wiggins JE, Wiggins RC. Hodgin JB, et al. J Am Soc Nephrol. 2015 Dec;26(12):3162-78. doi: 10.1681/ASN.2014080752. Epub 2015 Jun 2. J Am Soc Nephrol. 2015. PMID: 26038526 Free PMC article.
Organoid single cell profiling identifies a transcriptional signature of glomerular disease.
Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, O'Connor C, Luo J, Nair V, Cebrian C, Spence JR, Bitzer M, Troyanskaya OG, Hodgin JB, Wiggins RC, Freedman BS, Kretzler M; European Renal cDNA Bank (ERCB); Nephrotic Syndrome Study Network (NEPTUNE). Harder JL, et al. JCI Insight. 2019 Jan 10;4(1):e122697. doi: 10.1172/jci.insight.122697. JCI Insight. 2019. PMID: 30626756 Free PMC article.
Hypertension induces glomerulosclerosis in phospholipase C-ε1 deficiency.
Atchison DK, O'Connor CL, Menon R, Otto EA, Ganesh SK, Wiggins RC, Smrcka AV, Bitzer M. Atchison DK, et al. Am J Physiol Renal Physiol. 2020 May 1;318(5):F1177-F1187. doi: 10.1152/ajprenal.00541.2019. Epub 2020 Mar 30. Am J Physiol Renal Physiol. 2020. PMID: 32223311 Free PMC article.
SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth-onset type 2 diabetes.
Schaub JA, AlAkwaa FM, McCown PJ, Naik AS, Nair V, Eddy S, Menon R, Otto EA, Demeke D, Hartman J, Fermin D, O'Connor CL, Subramanian L, Bitzer M, Harned R, Ladd P, Pyle L, Pennathur S, Inoki K, Hodgin JB, Brosius FC 3rd, Nelson RG, Kretzler M, Bjornstad P. Schaub JA, et al. J Clin Invest. 2023 Mar 1;133(5):e164486. doi: 10.1172/JCI164486. J Clin Invest. 2023. PMID: 36637914 Free PMC article.
Spatial Heterogeneity of Glomerular Phenotypes Affects Kidney Biopsy Findings.
Schaub JA, O'Connor CL, Dailey M, Hlynka AW, Chang Y, Postiff D, Kaffenberger SD, Palapattu GS, Gillespie BW, Hodgin JB, Shedden K, Bitzer M. Schaub JA, et al. Kidney360. 2023 Nov 1;4(11):1598-1607. doi: 10.34067/KID.0000000000000283. Epub 2023 Oct 27. Kidney360. 2023. PMID: 37889598 Free PMC article.
2,434 results