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Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalization via macropinocytosis.
Derby SJ, Dutton L, Strathdee KE, Stevenson K, Koessinger A, Jackson M, Tian Y, Yu W, Mclay K, Misquitta J, Alsharif S, Clarke CJ, Gilmour L, Thomason P, McGhee E, McGarrity-Cottrell CL, Vanderlinden A, Collis SJ, Rominyi O, Lemgruber L, Solecki G, Olson M, Winkler F, Carlin LM, Heiland DH, Inman GJ, Chalmers AJ, Norman JC, Carruthers R, Birch JL. Derby SJ, et al. Among authors: jackson m. Neuro Oncol. 2024 Apr 5;26(4):625-639. doi: 10.1093/neuonc/noad210. Neuro Oncol. 2024. PMID: 37936324 Free PMC article.
Low-Dose Lung Radiation Therapy for COVID-19 Lung Disease: A Preclinical Efficacy Study in a Bleomycin Model of Pneumonitis.
Jackson MR, Stevenson K, Chahal SK, Curley E, Finney GE, Gutierrez-Quintana R, Onwubiko E, Rupp A, Strathdee K, Williams K, MacLeod MKL, McSharry C, Chalmers AJ. Jackson MR, et al. Int J Radiat Oncol Biol Phys. 2022 Jan 1;112(1):197-211. doi: 10.1016/j.ijrobp.2021.08.029. Epub 2021 Aug 31. Int J Radiat Oncol Biol Phys. 2022. PMID: 34478832 Free PMC article.
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics.
Koessinger AL, Cloix C, Koessinger D, Heiland DH, Bock FJ, Strathdee K, Kinch K, Martínez-Escardó L, Paul NR, Nixon C, Malviya G, Jackson MR, Campbell KJ, Stevenson K, Davis S, Elmasry Y, Ahmed A, O'Prey J, Ichim G, Schnell O, Stewart W, Blyth K, Ryan KM, Chalmers AJ, Norman JC, Tait SWG. Koessinger AL, et al. Among authors: jackson mr. Cell Death Differ. 2022 Oct;29(10):2089-2104. doi: 10.1038/s41418-022-01001-3. Epub 2022 Apr 26. Cell Death Differ. 2022. PMID: 35473984 Free PMC article.
Concurrent Olaparib and Radiation Therapy in Older Patients With Newly Diagnosed Glioblastoma: The Phase 1 Dose-Escalation PARADIGM Trial.
Derby S, Jackson MR, Williams K, Stobo J, Kelly C, Sweeting L, Shad S, Herbert C, Short SC, Williamson A, James A, Nowicki S, Bulbeck H, Chalmers AJ. Derby S, et al. Int J Radiat Oncol Biol Phys. 2024 Apr 1;118(5):1371-1378. doi: 10.1016/j.ijrobp.2024.01.011. Epub 2024 Jan 9. Int J Radiat Oncol Biol Phys. 2024. PMID: 38211641 Free article. Clinical Trial.
5,047 results