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Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors.
Wang Y, Parpia S, Couban R, Wang Q, Armijo-Olivo S, Bassler D, Briel M, Brignardello-Petersen R, Gluud LL, Keitz SA, Letelier LM, Ravaud P, Schulz KF, Siemieniuk RAC, Zeraatkar D, Guyatt GH. Wang Y, et al. Among authors: gluud ll. J Clin Epidemiol. 2024 Jan;165:111211. doi: 10.1016/j.jclinepi.2023.11.001. Epub 2023 Nov 7. J Clin Epidemiol. 2024. PMID: 37939743
Instruments assessing risk of bias of randomized trials frequently included items that are not addressing risk of bias issues.
Wang Y, Ghadimi M, Wang Q, Hou L, Zeraatkar D, Iqbal A, Ho C, Yao L, Hu M, Ye Z, Couban R, Armijo-Olivo S, Bassler D, Briel M, Gluud LL, Glasziou P, Jackson R, Keitz SA, Letelier LM, Ravaud P, Schulz KF, Siemieniuk RAC, Brignardello-Petersen R, Guyatt GH. Wang Y, et al. Among authors: gluud ll. J Clin Epidemiol. 2022 Dec;152:218-225. doi: 10.1016/j.jclinepi.2022.10.018. Epub 2022 Oct 28. J Clin Epidemiol. 2022. PMID: 36424692
Development of a novel non-invasive biomarker panel for hepatic fibrosis in MASLD.
Verschuren L, Mak AL, van Koppen A, Özsezen S, Difrancesco S, Caspers MPM, Snabel J, van der Meer D, van Dijk AM, Rashu EB, Nabilou P, Werge MP, van Son K, Kleemann R, Kiliaan AJ, Hazebroek EJ, Boonstra A, Brouwer WP, Doukas M, Gupta S, Kluft C, Nieuwdorp M, Verheij J, Gluud LL, Holleboom AG, Tushuizen ME, Hanemaaijer R. Verschuren L, et al. Among authors: gluud ll. Nat Commun. 2024 May 29;15(1):4564. doi: 10.1038/s41467-024-48956-0. Nat Commun. 2024. PMID: 38811591 Free PMC article.
New nomenclature for fatty liver disease.
Hansen CD, Lindvig KP, Grønbæk H, Gluud LL, Thiele M, Krag A. Hansen CD, et al. Among authors: gluud ll. Ugeskr Laeger. 2024 May 6;186(19):V12230778. doi: 10.61409/V12230778. Ugeskr Laeger. 2024. PMID: 38808766 Free article. Review. Danish.
Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study.
Winther-Sørensen M, Garcia SL, Bartholdy A, Ottenheijm ME, Banasik K, Brunak S, Sørensen CM, Gluud LL, Knop FK, Holst JJ, Rosenkilde MM, Jensen MK, Wewer Albrechtsen NJ. Winther-Sørensen M, et al. Among authors: gluud ll. Diabetologia. 2024 May 6. doi: 10.1007/s00125-024-06160-1. Online ahead of print. Diabetologia. 2024. PMID: 38705923
Glucagon augments the secretion of FGF21 and GDF15 in MASLD by indirect mechanisms.
Richter MM, Kemp IM, Heebøll S, Winther-Sørensen M, Kjeldsen SAS, Jensen NJ, Nybing JD, Linden FH, Høgh-Schmidt E, Boesen MP, Madsbad S, Schiødt FV, Nørgaard K, Schmidt S, Gluud LL, Haugaard SB, Holst JJ, Nielsen S, Rungby J, Wewer Albrechtsen NJ. Richter MM, et al. Among authors: gluud ll. Metabolism. 2024 Apr 16;156:155915. doi: 10.1016/j.metabol.2024.155915. Online ahead of print. Metabolism. 2024. PMID: 38631460 Free article.
Patients with autoimmune liver disease have glucose disturbances that mechanistically differ from steatotic liver disease.
Jensen AH, Ytting H, Werge MP, Rashu EB, Hetland LE, Thing M, Nabilou P, Burisch J, Bojsen-Møller KN, Junker AE, Hobolth L, Mortensen C, Tofteng F, Bendtsen F, Møller S, Vyberg M, Serizawa RR, Gluud LL, Wewer Albrechtsen NJ. Jensen AH, et al. Among authors: gluud ll. Am J Physiol Gastrointest Liver Physiol. 2024 Jun 1;326(6):G736-G746. doi: 10.1152/ajpgi.00047.2024. Epub 2024 Apr 16. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 38625142
222 results