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Bicyclo[m.n.k]alkane Building Blocks as Promising Benzene and Cycloalkane Isosteres: Multigram Synthesis, Physicochemical and Structural Characterization.
Semeno VV, Vasylchenko VO, Fesun IM, Ruzhylo LY, Kipriianov MO, Melnykov KP, Skreminskyi A, Iminov R, Mykhailiuk P, Vashchenko BV, Grygorenko OO. Semeno VV, et al. Among authors: melnykov kp. Chemistry. 2024 Feb 26;30(12):e202303859. doi: 10.1002/chem.202303859. Epub 2024 Jan 11. Chemistry. 2024. PMID: 38149408
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Boby ML, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson MC; COVID Moonshot Consortium‡; Chodera JD, Lee AA, London N, von Delft A, von Delft F, Achdout H, Aimon A, Alonzi DS, Arbon R, Aschenbrenner JC, Balcomb BH, Bar-David E, Barr H, Ben-Shmuel A, Bennett J, Bilenko VA, Borden B, Boulet P, Bowman GR, Brewitz L, Brun J, Bvnbs S, Calmiano M, Carbery A, Carney DW, Cattermole E, Chang E, Chernyshenko E, Clyde A, Coffland JE, Cohen G, Cole JC, Contini A, Cox L, Croll TI, Cvitkovic M, De Jonghe S, Dias A, Donckers K, Dotson DL, Douangamath A, Duberstein S, Dudgeon T, Dunnett LE, Eastman P, Erez N, Eyermann CJ, Fairhead M, Fate G, Fedorov O, Fernandes RS, Ferrins L, Foster R, Foster H, Fraisse L, Gabizon R, García-Sastre A, Gawriljuk VO, Gehrtz P, Gileadi C, Giroud C, Glass WG, Glen RC, Glinert I, Godoy AS, Gorichko M, Gorrie-Stone T, Griffen EJ, Haneef A, Hassell Hart S, Heer J, Henry M, Hill M, Horrell S, Huang QYJ, Huliak VD, Hurley MFD, Israely T, Jajack A, Jansen J, Jnoff E, Jochmans D, John T, Kaminow B, Kang L, Kantsadi AL, Kenny PW, Kiappes JL, Kinakh SO, Kovar B, Krojer T, La VNT, Laghnimi-Hahn S, Lefker BA, Levy H, Lithgo RM, Logvinenko IG, Lukacik P, Macdonald HB, MacLean … See abstract for full author list ➔ Boby ML, et al. Among authors: melnykov kp. Science. 2023 Nov 10;382(6671):eabo7201. doi: 10.1126/science.abo7201. Epub 2023 Nov 10. Science. 2023. PMID: 37943932 Free PMC article.
C-C Coupling through Nitrogen Deletion: Application to Library Synthesis.
Holovach S, Melnykov KP, Poroshyn I, Iminov RT, Dudenko D, Kondratov I, Levin M, Grygorenko OO. Holovach S, et al. Among authors: melnykov kp. Chemistry. 2023 Jan 18;29(4):e202204025. doi: 10.1002/chem.202204025. Epub 2023 Jan 4. Chemistry. 2023. PMID: 36599487
C-C Coupling through Nitrogen Deletion: Application to Library Synthesis.
Holovach S, Melnykov KP, Poroshyn I, Iminov RT, Dudenko D, Kondratov I, Levin M, Grygorenko OO. Holovach S, et al. Among authors: melnykov kp. Chemistry. 2023 Jan 18;29(4):e202203470. doi: 10.1002/chem.202203470. Epub 2022 Dec 21. Chemistry. 2023. PMID: 36445790
Fluorinated Cycloalkyl Building Blocks for Drug Discovery.
Grygorenko OO, Melnykov KP, Holovach S, Demchuk O. Grygorenko OO, et al. Among authors: melnykov kp. ChemMedChem. 2022 Nov 4;17(21):e202200365. doi: 10.1002/cmdc.202200365. Epub 2022 Oct 5. ChemMedChem. 2022. PMID: 36031924 Review.
Scalable Synthesis of Biologically Relevant Spirocyclic Pyrrolidines.
Melnykov KP, Artemenko AN, Ivanenko BO, Sokolenko YM, Nosik PS, Ostapchuk EN, Grygorenko OO, Volochnyuk DM, Ryabukhin SV. Melnykov KP, et al. ACS Omega. 2019 Apr 24;4(4):7498-7515. doi: 10.1021/acsomega.9b00896. eCollection 2019 Apr 30. ACS Omega. 2019. PMID: 31459845 Free PMC article.
12 results