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The chemotherapeutic agent doxorubicin induces brain senescence, with modulation by APOE genotype.
Exp Neurol. 2024 Jan;371:114609. doi: 10.1016/j.expneurol.2023.114609. Epub 2023 Nov 7.
Exp Neurol. 2024.
PMID: 37944881
Free article.
A mouse model of chemotherapy-related cognitive impairments integrating the risk factors of aging and APOE4 genotype.
Demby TC, Rodriguez O, McCarthy CW, Lee YC, Albanese C, Mandelblatt J, Rebeck GW.
Demby TC, et al.
Behav Brain Res. 2020 Apr 20;384:112534. doi: 10.1016/j.bbr.2020.112534. Epub 2020 Feb 3.
Behav Brain Res. 2020.
PMID: 32027870
Free PMC article.
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Development of a Human APOE Knock-in Mouse Model for Study of Cognitive Function After Cancer Chemotherapy.
Speidell AP, Demby T, Lee Y, Rodriguez O, Albanese C, Mandelblatt J, Rebeck GW.
Speidell AP, et al. Among authors: demby t.
Neurotox Res. 2019 Feb;35(2):291-303. doi: 10.1007/s12640-018-9954-7. Epub 2018 Oct 4.
Neurotox Res. 2019.
PMID: 30284204
Free PMC article.
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