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Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples.
O'Donnell VB, Schebb NH, Milne GL, Murphy MP, Thomas CP, Steinhilber D, Gelhaus SL, Kühn H, Gelb MH, Jakobsson PJ, Blair IA, Murphy RC, Freeman BA, Brash AR, FitzGerald GA. O'Donnell VB, et al. Among authors: murphy rc, murphy mp. Nat Commun. 2023 Nov 9;14(1):7172. doi: 10.1038/s41467-023-41766-w. Nat Commun. 2023. PMID: 37945602 Free PMC article. No abstract available.
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo.
Murphy MP, Bayir H, Belousov V, Chang CJ, Davies KJA, Davies MJ, Dick TP, Finkel T, Forman HJ, Janssen-Heininger Y, Gems D, Kagan VE, Kalyanaraman B, Larsson NG, Milne GL, Nyström T, Poulsen HE, Radi R, Van Remmen H, Schumacker PT, Thornalley PJ, Toyokuni S, Winterbourn CC, Yin H, Halliwell B. Murphy MP, et al. Nat Metab. 2022 Jun;4(6):651-662. doi: 10.1038/s42255-022-00591-z. Epub 2022 Jun 27. Nat Metab. 2022. PMID: 35760871 Free PMC article. Review.
Malonylation of GAPDH is an inflammatory signal in macrophages.
Galván-Peña S, Carroll RG, Newman C, Hinchy EC, Palsson-McDermott E, Robinson EK, Covarrubias S, Nadin A, James AM, Haneklaus M, Carpenter S, Kelly VP, Murphy MP, Modis LK, O'Neill LA. Galván-Peña S, et al. Among authors: murphy mp. Nat Commun. 2019 Jan 18;10(1):338. doi: 10.1038/s41467-018-08187-6. Nat Commun. 2019. PMID: 30659183 Free PMC article.
Structural basis for a complex I mutation that blocks pathological ROS production.
Yin Z, Burger N, Kula-Alwar D, Aksentijević D, Bridges HR, Prag HA, Grba DN, Viscomi C, James AM, Mottahedin A, Krieg T, Murphy MP, Hirst J. Yin Z, et al. Among authors: murphy mp. Nat Commun. 2021 Jan 29;12(1):707. doi: 10.1038/s41467-021-20942-w. Nat Commun. 2021. PMID: 33514727 Free PMC article.
Mitochondrial complex I activity in microglia sustains neuroinflammation.
Peruzzotti-Jametti L, Willis CM, Krzak G, Hamel R, Pirvan L, Ionescu RB, Reisz JA, Prag HA, Garcia-Segura ME, Wu V, Xiang Y, Barlas B, Casey AM, van den Bosch AMR, Nicaise AM, Roth L, Bates GR, Huang H, Prasad P, Vincent AE, Frezza C, Viscomi C, Balmus G, Takats Z, Marioni JC, D'Alessandro A, Murphy MP, Mohorianu I, Pluchino S. Peruzzotti-Jametti L, et al. Among authors: murphy mp. Nature. 2024 Apr;628(8006):195-203. doi: 10.1038/s41586-024-07167-9. Epub 2024 Mar 13. Nature. 2024. PMID: 38480879 Free PMC article.
A redox switch in angiotensinogen modulates angiotensin release.
Zhou A, Carrell RW, Murphy MP, Wei Z, Yan Y, Stanley PL, Stein PE, Broughton Pipkin F, Read RJ. Zhou A, et al. Among authors: murphy mp. Nature. 2010 Nov 4;468(7320):108-11. doi: 10.1038/nature09505. Epub 2010 Oct 6. Nature. 2010. PMID: 20927107 Free PMC article.
795 results