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Spatial and single-cell profiling of the metabolome, transcriptome and epigenome of the aging mouse liver.
Nikopoulou C, Kleinenkuhnen N, Parekh S, Sandoval T, Ziegenhain C, Schneider F, Giavalisco P, Donahue KF, Vesting AJ, Kirchner M, Bozukova M, Vossen C, Altmüller J, Wunderlich T, Sandberg R, Kondylis V, Tresch A, Tessarz P. Nikopoulou C, et al. Among authors: giavalisco p. Nat Aging. 2023 Nov;3(11):1430-1445. doi: 10.1038/s43587-023-00513-y. Epub 2023 Nov 9. Nat Aging. 2023. PMID: 37946043 Free PMC article.
Alzheimer's brains show inter-related changes in RNA and lipid metabolism.
Barbash S, Garfinkel BP, Maoz R, Simchovitz A, Nadorp B, Guffanti A, Bennett ER, Nadeau C, Türk A, Paul L, Reda T, Li Y, Buchman AS, Greenberg DS, Seitz A, Bennett DA, Giavalisco P, Soreq H. Barbash S, et al. Among authors: giavalisco p. Neurobiol Dis. 2017 Oct;106:1-13. doi: 10.1016/j.nbd.2017.06.008. Epub 2017 Jun 17. Neurobiol Dis. 2017. PMID: 28630030 Free PMC article.
Organization and evolution of brain lipidome revealed by large-scale analysis of human, chimpanzee, macaque, and mouse tissues.
Bozek K, Wei Y, Yan Z, Liu X, Xiong J, Sugimoto M, Tomita M, Pääbo S, Sherwood CC, Hof PR, Ely JJ, Li Y, Steinhauser D, Willmitzer L, Giavalisco P, Khaitovich P. Bozek K, et al. Among authors: giavalisco p. Neuron. 2015 Feb 18;85(4):695-702. doi: 10.1016/j.neuron.2015.01.003. Epub 2015 Feb 5. Neuron. 2015. PMID: 25661180 Free article.
Small-molecule inhibitors of human mitochondrial DNA transcription.
Bonekamp NA, Peter B, Hillen HS, Felser A, Bergbrede T, Choidas A, Horn M, Unger A, Di Lucrezia R, Atanassov I, Li X, Koch U, Menninger S, Boros J, Habenberger P, Giavalisco P, Cramer P, Denzel MS, Nussbaumer P, Klebl B, Falkenberg M, Gustafsson CM, Larsson NG. Bonekamp NA, et al. Among authors: giavalisco p. Nature. 2020 Dec;588(7839):712-716. doi: 10.1038/s41586-020-03048-z. Epub 2020 Dec 16. Nature. 2020. PMID: 33328633
Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity.
Sprenger HG, MacVicar T, Bahat A, Fiedler KU, Hermans S, Ehrentraut D, Ried K, Milenkovic D, Bonekamp N, Larsson NG, Nolte H, Giavalisco P, Langer T. Sprenger HG, et al. Among authors: giavalisco p. Nat Metab. 2021 May;3(5):636-650. doi: 10.1038/s42255-021-00385-9. Epub 2021 Apr 26. Nat Metab. 2021. PMID: 33903774 Free PMC article.
Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices.
Alseekh S, Aharoni A, Brotman Y, Contrepois K, D'Auria J, Ewald J, C Ewald J, Fraser PD, Giavalisco P, Hall RD, Heinemann M, Link H, Luo J, Neumann S, Nielsen J, Perez de Souza L, Saito K, Sauer U, Schroeder FC, Schuster S, Siuzdak G, Skirycz A, Sumner LW, Snyder MP, Tang H, Tohge T, Wang Y, Wen W, Wu S, Xu G, Zamboni N, Fernie AR. Alseekh S, et al. Among authors: giavalisco p. Nat Methods. 2021 Jul;18(7):747-756. doi: 10.1038/s41592-021-01197-1. Epub 2021 Jul 8. Nat Methods. 2021. PMID: 34239102 Free PMC article. Review.
Toward the storage metabolome: profiling the barley vacuole.
Tohge T, Ramos MS, Nunes-Nesi A, Mutwil M, Giavalisco P, Steinhauser D, Schellenberg M, Willmitzer L, Persson S, Martinoia E, Fernie AR. Tohge T, et al. Among authors: giavalisco p. Plant Physiol. 2011 Nov;157(3):1469-82. doi: 10.1104/pp.111.185710. Epub 2011 Sep 26. Plant Physiol. 2011. PMID: 21949213 Free PMC article.
136 results