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Vitamin B5 supports MYC oncogenic metabolism and tumor progression in breast cancer.
Kreuzaler P, Inglese P, Ghanate A, Gjelaj E, Wu V, Panina Y, Mendez-Lucas A, MacLachlan C, Patani N, Hubert CB, Huang H, Greenidge G, Rueda OM, Taylor AJ, Karali E, Kazanc E, Spicer A, Dexter A, Lin W, Thompson D, Silva Dos Santos M, Calvani E, Legrave N, Ellis JK, Greenwood W, Green M, Nye E, Still E; CRUK Rosetta Grand Challenge Consortium; Barry S, Goodwin RJA, Bruna A, Caldas C, MacRae J, de Carvalho LPS, Poulogiannis G, McMahon G, Takats Z, Bunch J, Yuneva M. Kreuzaler P, et al. Nat Metab. 2023 Nov;5(11):1870-1886. doi: 10.1038/s42255-023-00915-7. Epub 2023 Nov 9. Nat Metab. 2023. PMID: 37946084 Free PMC article.
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
Najumudeen AK, Ceteci F, Fey SK, Hamm G, Steven RT, Hall H, Nikula CJ, Dexter A, Murta T, Race AM, Sumpton D, Vlahov N, Gay DM, Knight JRP, Jackstadt R, Leach JDG, Ridgway RA, Johnson ER, Nixon C, Hedley A, Gilroy K, Clark W, Malla SB, Dunne PD, Rodriguez-Blanco G, Critchlow SE, Mrowinska A, Malviya G, Solovyev D, Brown G, Lewis DY, Mackay GM, Strathdee D, Tardito S, Gottlieb E; CRUK Rosetta Grand Challenge Consortium; Takats Z, Barry ST, Goodwin RJA, Bunch J, Bushell M, Campbell AD, Sansom OJ. Najumudeen AK, et al. Nat Genet. 2021 Jan;53(1):16-26. doi: 10.1038/s41588-020-00753-3. Epub 2021 Jan 7. Nat Genet. 2021. PMID: 33414552
Killing a cancer: what are the alternatives?
Kreuzaler P, Watson CJ. Kreuzaler P, et al. Nat Rev Cancer. 2012 May 11;12(6):411-24. doi: 10.1038/nrc3264. Nat Rev Cancer. 2012. PMID: 22576162 Review.
The role of cathepsins in involution and breast cancer.
Watson CJ, Kreuzaler PA. Watson CJ, et al. J Mammary Gland Biol Neoplasia. 2009 Jun;14(2):171-9. doi: 10.1007/s10911-009-9126-8. Epub 2009 May 13. J Mammary Gland Biol Neoplasia. 2009. PMID: 19437107
Stat3 controls lysosomal-mediated cell death in vivo.
Kreuzaler PA, Staniszewska AD, Li W, Omidvar N, Kedjouar B, Turkson J, Poli V, Flavell RA, Clarkson RW, Watson CJ. Kreuzaler PA, et al. Nat Cell Biol. 2011 Mar;13(3):303-9. doi: 10.1038/ncb2171. Epub 2011 Feb 20. Nat Cell Biol. 2011. PMID: 21336304
All things to all people.
Littlewood TD, Kreuzaler P, Evan GI. Littlewood TD, et al. Among authors: kreuzaler p. Cell. 2012 Sep 28;151(1):11-3. doi: 10.1016/j.cell.2012.09.006. Cell. 2012. PMID: 23021211 Free article.
ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis.
Hennequart M, Pilley SE, Labuschagne CF, Coomes J, Mervant L, Driscoll PC, Legrave NM, Lee Y, Kreuzaler P, Macintyre B, Panina Y, Blagih J, Stevenson D, Strathdee D, Schneider-Luftman D, Grönroos E, Cheung EC, Yuneva M, Swanton C, Vousden KH. Hennequart M, et al. Among authors: kreuzaler p. Cell Rep. 2023 Jun 27;42(6):112562. doi: 10.1016/j.celrep.2023.112562. Epub 2023 May 26. Cell Rep. 2023. PMID: 37245210 Free article.
Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age - a multicenter retrospective study.
Saffari A, Brösse I, Wiemer-Kruel A, Wilken B, Kreuzaler P, Hahn A, Bernhard MK, van Tilburg CM, Hoffmann GF, Gorenflo M, Hethey S, Kaiser O, Kölker S, Wagner R, Witt O, Merkenschlager A, Möckel A, Roser T, Schlump JU, Serfling A, Spiegler J, Milde T, Ziegler A, Syrbe S. Saffari A, et al. Among authors: kreuzaler p. Orphanet J Rare Dis. 2019 May 3;14(1):96. doi: 10.1186/s13023-019-1077-6. Orphanet J Rare Dis. 2019. PMID: 31053163 Free PMC article.
18 results