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Page 1
Artificial intelligence-based pathology as a biomarker of sensitivity to atezolizumab-bevacizumab in patients with hepatocellular carcinoma: a multicentre retrospective study.
Zeng Q, Klein C, Caruso S, Maille P, Allende DS, Mínguez B, Iavarone M, Ningarhari M, Casadei-Gardini A, Pedica F, Rimini M, Perbellini R, Boulagnon-Rombi C, Heurgué A, Maggioni M, Rela M, Vij M, Baulande S, Legoix P, Lameiras S; HCC-AI study group; Bruges L, Gnemmi V, Nault JC, Campani C, Rhee H, Park YN, Iñarrairaegui M, Garcia-Porrero G, Argemi J, Sangro B, D'Alessio A, Scheiner B, Pinato DJ, Pinter M, Paradis V, Beaufrère A, Peter S, Rimassa L, Di Tommaso L, Vogel A, Michalak S, Boursier J, Loménie N, Ziol M, Calderaro J. Zeng Q, et al. Among authors: legoix p. Lancet Oncol. 2023 Dec;24(12):1411-1422. doi: 10.1016/S1470-2045(23)00468-0. Epub 2023 Nov 8. Lancet Oncol. 2023. PMID: 37951222
EZH2 mutations in follicular lymphoma distort H3K27me3 profiles and alter transcriptional responses to PRC2 inhibition.
Romero P, Richart L, Aflaki S, Petitalot A, Burton M, Michaud A, Masliah-Planchon J, Kuhnowski F, Le Cam S, Baliñas-Gavira C, Méaudre C, Luscan A, Hamza A, Legoix P, Vincent-Salomon A, Wassef M, Holoch D, Margueron R. Romero P, et al. Among authors: legoix p. Nat Commun. 2024 Apr 24;15(1):3452. doi: 10.1038/s41467-024-47701-x. Nat Commun. 2024. PMID: 38658543 Free PMC article.
VC-resist glioblastoma cell state: vessel co-option as a key driver of chemoradiation resistance.
Pichol-Thievend C, Anezo O, Pettiwala AM, Bourmeau G, Montagne R, Lyne AM, Guichet PO, Deshors P, Ballestín A, Blanchard B, Reveilles J, Ravi VM, Joseph K, Heiland DH, Julien B, Leboucher S, Besse L, Legoix P, Dingli F, Liva S, Loew D, Giani E, Ribecco V, Furumaya C, Marcos-Kovandzic L, Masliantsev K, Daubon T, Wang L, Diaz AA, Schnell O, Beck J, Servant N, Karayan-Tapon L, Cavalli FMG, Seano G. Pichol-Thievend C, et al. Among authors: legoix p. Nat Commun. 2024 Apr 29;15(1):3602. doi: 10.1038/s41467-024-47985-z. Nat Commun. 2024. PMID: 38684700 Free PMC article.
Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes.
Alraies Z, Rivera CA, Delgado MG, Sanséau D, Maurin M, Amadio R, Maria Piperno G, Dunsmore G, Yatim A, Lacerda Mariano L, Kniazeva A, Calmettes V, Sáez PJ, Williart A, Popard H, Gratia M, Lamiable O, Moreau A, Fusilier Z, Crestey L, Albaud B, Legoix P, Dejean AS, Le Dorze AL, Nakano H, Cook DN, Lawrence T, Manel N, Benvenuti F, Ginhoux F, Moreau HD, P F Nader G, Piel M, Lennon-Duménil AM. Alraies Z, et al. Among authors: legoix p. Nat Immunol. 2024 Jun 4. doi: 10.1038/s41590-024-01856-3. Online ahead of print. Nat Immunol. 2024. PMID: 38834865
Early macrophage response to obesity encompasses Interferon Regulatory Factor 5 regulated mitochondrial architecture remodelling.
Orliaguet L, Ejlalmanesh T, Humbert A, Ballaire R, Diedisheim M, Julla JB, Chokr D, Cuenco J, Michieletto J, Charbit J, Lindén D, Boucher J, Potier C, Hamimi A, Lemoine S, Blugeon C, Legoix P, Lameiras S, Baudrin LG, Baulande S, Soprani A, Castelli FA, Fenaille F, Riveline JP, Dalmas E, Rieusset J, Gautier JF, Venteclef N, Alzaid F. Orliaguet L, et al. Among authors: legoix p. Nat Commun. 2022 Aug 30;13(1):5089. doi: 10.1038/s41467-022-32813-z. Nat Commun. 2022. PMID: 36042203 Free PMC article.
A novel 3D culture model recapitulates primary FL B-cell features and promotes their survival.
Lamaison C, Latour S, Hélaine N, Le Morvan V, Saint-Vanne J, Mahouche I, Monvoisin C, Dussert C, Andrique L, Deleurme L, Dessauge E, Pangault C, Baulande S, Legoix P, Seffals M, Broca-Brisson L, Alessandri K, Carlotti M, Soubeyran P, Merlio JP, Mourcin F, Nassoy P, Recher G, Tarte K, Bresson-Bepoldin L. Lamaison C, et al. Among authors: legoix p. Blood Adv. 2021 Dec 14;5(23):5372-5386. doi: 10.1182/bloodadvances.2020003949. Blood Adv. 2021. PMID: 34555842 Free PMC article.
Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape.
Mourcin F, Verdiére L, Roulois D, Amin R, Lamaison C, Sibut V, Thamphya B, Pangault C, Monvoisin C, Huet S, Seffals M, Baulande S, Mechta-Grigoriou F, Legoix P, Rossille D, Guirriec M, Léonard S, Cartron G, Salles G, Fest T, Tarte K. Mourcin F, et al. Among authors: legoix p. Immunity. 2021 Aug 10;54(8):1901. doi: 10.1016/j.immuni.2021.07.018. Immunity. 2021. PMID: 34380065 Free article. No abstract available.
Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape.
Mourcin F, Verdière L, Roulois D, Amin R, Lamaison C, Sibut V, Thamphya B, Pangault C, Monvoisin C, Huet S, Seffals M, Baulande S, Mechta-Grigoriou F, Legoix P, Rossille D, Guirriec M, Léonard S, Cartron G, Salles G, Fest T, Tarte K. Mourcin F, et al. Among authors: legoix p. Immunity. 2021 Aug 10;54(8):1788-1806.e7. doi: 10.1016/j.immuni.2021.05.019. Epub 2021 Jun 23. Immunity. 2021. PMID: 34166622 Free article.
Prognostic value of tumor mutational burden in patients with oral cavity squamous cell carcinoma treated with upfront surgery.
Moreira A, Poulet A, Masliah-Planchon J, Lecerf C, Vacher S, Larbi Chérif L, Dupain C, Marret G, Girard E, Syx L, Hoffmann C, Jeannot E, Klijanienko J, Guillou I, Mariani O, Dubray-Vautrin A, Badois N, Lesnik M, Choussy O, Calugaru V, Borcoman E, Baulande S, Legoix P, Albaud B, Servant N, Bieche I, Le Tourneau C, Kamal M. Moreira A, et al. Among authors: legoix p. ESMO Open. 2021 Aug;6(4):100178. doi: 10.1016/j.esmoop.2021.100178. Epub 2021 Jun 9. ESMO Open. 2021. PMID: 34118772 Free PMC article.
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