Rosenspire AJ - Search Results

1

Naturally occurring autoimmune disease in (NZB X NZW) F1 mice is correlated with suppression of MZ B cell development due to aberrant B Cell Receptor (BCR) signaling, which is exacerbated by exposure to inorganic mercury.

Gill RF, Mathieu PA, Lash LH, Rosenspire AJ. Gill RF, et al. Among authors: rosenspire aj. Toxicol Sci. 2023 Nov 11;197(2):211-21. doi: 10.1093/toxsci/kfad120. Online ahead of print. Toxicol Sci. 2023. PMID: 37952249

2

Mercury intoxication disrupts tonic signaling in B cells, and may promote autoimmunity due to abnormal phosphorylation of STIM-1 and other autoimmunity risk associated phosphoproteins involved in BCR signaling.

Carruthers NJ, Guo C, Gill R, Stemmer PM, Rosenspire AJ. Carruthers NJ, et al. Among authors: rosenspire aj. Toxicol Appl Pharmacol. 2023 Sep 1;474:116607. doi: 10.1016/j.taap.2023.116607. Epub 2023 Jun 20. Toxicol Appl Pharmacol. 2023. PMID: 37348680

3

At low levels, inorganic mercury interference with antigen signaling is associated with modifications to a panel of novel phosphoserine sites in B cell receptor pathway proteins.

Guo C, Mattingly RR, Stemmer PM, Rosenspire AJ. Guo C, et al. Among authors: rosenspire aj. Toxicol In Vitro. 2023 Jun;89:105564. doi: 10.1016/j.tiv.2023.105564. Epub 2023 Feb 2. Toxicol In Vitro. 2023. PMID: 36736710

4

Editorial: The Role of the Environment in Autoimmunity.

Pestka JJ, Pollard KM, Rosenspire AJ. Pestka JJ, et al. Among authors: rosenspire aj. Front Immunol. 2021 Feb 22;12:641171. doi: 10.3389/fimmu.2021.641171. eCollection 2021. Front Immunol. 2021. PMID: 33692809 Free PMC article. No abstract available.

5

Low level Hg²⁺ exposure modulates the B-cell cytoskeletal phosphoproteome.

Carruthers NJ, Rosenspire AJ, Caruso JA, Stemmer PM. Carruthers NJ, et al. Among authors: rosenspire aj. J Proteomics. 2018 Feb 20;173:107-114. doi: 10.1016/j.jprot.2017.11.026. Epub 2017 Dec 2. J Proteomics. 2018. PMID: 29199152

6

Low level exposure to inorganic mercury interferes with B cell receptor signaling in transitional type 1 B cells.

Gill R, McCabe MJ Jr, Rosenspire AJ. Gill R, et al. Among authors: rosenspire aj. Toxicol Appl Pharmacol. 2017 Sep 1;330:22-29. doi: 10.1016/j.taap.2017.06.022. Epub 2017 Jun 28. Toxicol Appl Pharmacol. 2017. PMID: 28668464 Free PMC article.

7

Anergic B Cells: Precarious On-Call Warriors at the Nexus of Autoimmunity and False-Flagged Pathogens.

Rosenspire AJ, Chen K. Rosenspire AJ, et al. Front Immunol. 2015 Nov 26;6:580. doi: 10.3389/fimmu.2015.00580. eCollection 2015. Front Immunol. 2015. PMID: 26635794 Free PMC article. Review. No abstract available.

8

Elements of the B cell signalosome are differentially affected by mercury intoxication.

Gill RF, McCabe MJ, Rosenspire AJ. Gill RF, et al. Among authors: rosenspire aj. Autoimmune Dis. 2014;2014:239358. doi: 10.1155/2014/239358. Epub 2014 May 4. Autoimmune Dis. 2014. PMID: 24876949 Free PMC article.

9

A systems toxicology approach identifies Lyn as a key signaling phosphoprotein modulated by mercury in a B lymphocyte cell model.

Caruso JA, Stemmer PM, Dombkowski A, Caruthers NJ, Gill R, Rosenspire AJ. Caruso JA, et al. Among authors: rosenspire aj. Toxicol Appl Pharmacol. 2014 Apr 1;276(1):47-54. doi: 10.1016/j.taap.2014.01.002. Epub 2014 Jan 14. Toxicol Appl Pharmacol. 2014. PMID: 24440445 Free PMC article.

10

HLA Immune Function Genes in Autism.

Torres AR, Westover JB, Rosenspire AJ. Torres AR, et al. Among authors: rosenspire aj. Autism Res Treat. 2012;2012:959073. doi: 10.1155/2012/959073. Epub 2012 Feb 15. Autism Res Treat. 2012. PMID: 22928105 Free PMC article.

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