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Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function.
Xu W, Billon C, Li H, Wilderman A, Qi L, Graves A, Rideb JRDC, Zhao Y, Hayes M, Yu K, Losby M, Hampton CS, Adeyemi CM, Hong SJ, Nasiotis E, Fu C, Oh TG, Fan W, Downes M, Welch RD, Evans RM, Milosavljevic A, Walker JK, Jensen BC, Pei L, Burris T, Zhang L. Xu W, et al. Among authors: hayes m. Circulation. 2024 Jan 16;149(3):227-250. doi: 10.1161/CIRCULATIONAHA.123.066542. Epub 2023 Nov 14. Circulation. 2024. PMID: 37961903
Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity.
Billon C, Sitaula S, Banerjee S, Welch R, Elgendy B, Hegazy L, Oh TG, Kazantzis M, Chatterjee A, Chrivia J, Hayes ME, Xu W, Hamilton A, Huss JM, Zhang L, Walker JK, Downes M, Evans RM, Burris TP. Billon C, et al. Among authors: hayes me. ACS Chem Biol. 2023 Apr 21;18(4):756-771. doi: 10.1021/acschembio.2c00720. Epub 2023 Mar 29. ACS Chem Biol. 2023. PMID: 36988910
The role of REV-ERB in NASH.
Griffett K, Hayes ME, Boeckman MP, Burris TP. Griffett K, et al. Acta Pharmacol Sin. 2022 May;43(5):1133-1140. doi: 10.1038/s41401-022-00883-w. Epub 2022 Feb 25. Acta Pharmacol Sin. 2022. PMID: 35217816 Free PMC article.
Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists.
Griffett K, Hayes M, Bedia-Diaz G, Appourchaux K, Sanders R, Boeckman MP, Koelblen T, Zhang J, Schulman IG, Elgendy B, Burris TP. Griffett K, et al. Among authors: hayes m. ACS Chem Biol. 2022 May 20;17(5):1143-1154. doi: 10.1021/acschembio.2c00057. Epub 2022 Apr 13. ACS Chem Biol. 2022. PMID: 35417135
Circadian clock protein Rev-erbα regulates neuroinflammation.
Griffin P, Dimitry JM, Sheehan PW, Lananna BV, Guo C, Robinette ML, Hayes ME, Cedeño MR, Nadarajah CJ, Ezerskiy LA, Colonna M, Zhang J, Bauer AQ, Burris TP, Musiek ES. Griffin P, et al. Among authors: hayes me. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5102-5107. doi: 10.1073/pnas.1812405116. Epub 2019 Feb 21. Proc Natl Acad Sci U S A. 2019. PMID: 30792350 Free PMC article.
Single Cell Profiling Distinguishes Leukemia-Selective Chemotypes.
Thirman HL, Hayes MJ, Brown LE, Porco JA, Irish JM. Thirman HL, et al. Among authors: hayes mj. bioRxiv [Preprint]. 2024 May 3:2024.05.01.591362. doi: 10.1101/2024.05.01.591362. bioRxiv. 2024. PMID: 38826485 Free PMC article. Preprint.
Early trajectories of virological and immunological biomarkers and clinical outcomes in patients admitted to hospital for COVID-19: an international, prospective cohort study.
Jensen TO, Murray TA, Grandits GA, Jain MK, Grund B, Shaw-Saliba K, Matthay MA, Abassi M, Ardelt M, Baker JV, Chen P, Dewar RL, Goodman AL, Hatlen TJ, Highbarger HC, Holodniy M, Lallemand P, Laverdure S, Leshnower BG, Looney D, Moschopoulos CD, Mugerwa H, Murray DD, Mylonakis E, Nagy-Agren S, Rehman MT, Rupert A, Stevens R, Turville S, Weintrob A, Wick K, Lundgren J, Ko ER; ACTIV-3/TICO Study Group. Jensen TO, et al. Lancet Microbe. 2024 May 27:S2666-5247(24)00015-6. doi: 10.1016/S2666-5247(24)00015-6. Online ahead of print. Lancet Microbe. 2024. PMID: 38815595 Free article.
2,477 results