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Raising NAD+ Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation.
Walker MA, Chen H, Yadav A, Ritterhoff J, Villet O, McMillen T, Wang Y, Purcell H, Djukovic D, Raftery D, Isoherranen N, Tian R. Walker MA, et al. Among authors: wang y. Circulation. 2023 Dec 19;148(25):2038-2057. doi: 10.1161/CIRCULATIONAHA.123.066039. Epub 2023 Nov 15. Circulation. 2023. PMID: 37965787
Fatty Acids Enhance the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells.
Yang X, Rodriguez ML, Leonard A, Sun L, Fischer KA, Wang Y, Ritterhoff J, Zhao L, Kolwicz SC Jr, Pabon L, Reinecke H, Sniadecki NJ, Tian R, Ruohola-Baker H, Xu H, Murry CE. Yang X, et al. Among authors: wang y. Stem Cell Reports. 2019 Oct 8;13(4):657-668. doi: 10.1016/j.stemcr.2019.08.013. Epub 2019 Sep 26. Stem Cell Reports. 2019. PMID: 31564645 Free PMC article.
Amino acid primed mTOR activity is essential for heart regeneration.
Miklas JW, Levy S, Hofsteen P, Mex DI, Clark E, Muster J, Robitaille AM, Sivaram G, Abell L, Goodson JM, Pranoto I, Madan A, Chin MT, Tian R, Murry CE, Moon RT, Wang Y, Ruohola-Baker H. Miklas JW, et al. Among authors: wang y. iScience. 2021 Dec 6;25(1):103574. doi: 10.1016/j.isci.2021.103574. eCollection 2022 Jan 21. iScience. 2021. PMID: 34988408 Free PMC article.
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes.
Miklas JW, Clark E, Levy S, Detraux D, Leonard A, Beussman K, Showalter MR, Smith AT, Hofsteen P, Yang X, Macadangdang J, Manninen T, Raftery D, Madan A, Suomalainen A, Kim DH, Murry CE, Fiehn O, Sniadecki NJ, Wang Y, Ruohola-Baker H. Miklas JW, et al. Among authors: wang y. Nat Commun. 2019 Oct 11;10(1):4671. doi: 10.1038/s41467-019-12482-1. Nat Commun. 2019. PMID: 31604922 Free PMC article.
Author Correction: TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes.
Miklas JW, Clark E, Levy S, Detraux D, Leonard A, Beussman K, Showalter MR, Smith AT, Hofsteen P, Yang X, Macadangdang J, Manninen T, Raftery D, Madan A, Suomalainen A, Kim DH, Murry CE, Fiehn O, Sniadecki NJ, Wang Y, Ruohola-Baker H. Miklas JW, et al. Among authors: wang y. Nat Commun. 2020 May 8;11(1):2387. doi: 10.1038/s41467-020-16186-9. Nat Commun. 2020. PMID: 32385292 Free PMC article.
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H. Sperber H, et al. Among authors: wang y. Nat Cell Biol. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16. Nat Cell Biol. 2015. PMID: 26571212 Free PMC article.
microRNAs Regulating Human and Mouse Naïve Pluripotency.
Wang Y, Hussein AM, Somasundaram L, Sankar R, Detraux D, Mathieu J, Ruohola-Baker H. Wang Y, et al. Int J Mol Sci. 2019 Nov 22;20(23):5864. doi: 10.3390/ijms20235864. Int J Mol Sci. 2019. PMID: 31766734 Free PMC article.
Global transcriptomic changes occur in aged mouse podocytes.
Wang Y, Eng DG, Kaverina NV, Loretz CJ, Koirala A, Akilesh S, Pippin JW, Shankland SJ. Wang Y, et al. Kidney Int. 2020 Nov;98(5):1160-1173. doi: 10.1016/j.kint.2020.05.052. Epub 2020 Jun 25. Kidney Int. 2020. PMID: 32592814 Free PMC article.
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