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Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362.
Lowe MA, Cardenas A, Valentin JP, Zhu Z, Abendroth J, Castro JL, Class R, Delaunois A, Fleurance R, Gerets H, Gryshkova V, King L, Lorimer DD, MacCoss M, Rowley JH, Rosseels ML, Royer L, Taylor RD, Wong M, Zaccheo O, Chavan VP, Ghule GA, Tapkir BK, Burrows JN, Duffey M, Rottmann M, Wittlin S, Angulo-Barturen I, Jiménez-Díaz MB, Striepen J, Fairhurst KJ, Yeo T, Fidock DA, Cowman AF, Favuzza P, Crespo-Fernandez B, Gamo FJ, Goldberg DE, Soldati-Favre D, Laleu B, de Haro T. Lowe MA, et al. Among authors: king l. J Med Chem. 2022 Oct 27;65(20):14121-14143. doi: 10.1021/acs.jmedchem.2c01336. Epub 2022 Oct 10. J Med Chem. 2022. PMID: 36216349 Free PMC article.
Discovery of 4-azaindoles as novel inhibitors of c-Met kinase.
Porter J, Lumb S, Franklin RJ, Gascon-Simorte JM, Calmiano M, Riche KL, Lallemand B, Keyaerts J, Edwards H, Maloney A, Delgado J, King L, Foley A, Lecomte F, Reuberson J, Meier C, Batchelor M. Porter J, et al. Among authors: king l. Bioorg Med Chem Lett. 2009 May 15;19(10):2780-4. doi: 10.1016/j.bmcl.2009.03.110. Epub 2009 Mar 27. Bioorg Med Chem Lett. 2009. PMID: 19369077
Improving eSource Site Start-Up Practices.
Cramer AE, King LS, Buckley MT, Casteleyn P, Ennis C, Hamidi M, Rodrigues GMC, Snyder DC, Vattikola A, Eisenstein EL. Cramer AE, et al. Among authors: king ls. Res Sq [Preprint]. 2024 May 24:rs.3.rs-4414917. doi: 10.21203/rs.3.rs-4414917/v1. Res Sq. 2024. PMID: 38826202 Free PMC article. Preprint.
3,044 results