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ESR1 F404 Mutations and Acquired Resistance to Fulvestrant in ESR1-Mutant Breast Cancer.
Kingston B, Pearson A, Herrera-Abreu MT, Sim LX, Cutts RJ, Shah H, Moretti L, Kilburn LS, Johnson H, Macpherson IR, Ring A, Bliss JM, Hou Y, Toy W, Katzenellenbogen JA, Chandarlapaty S, Turner NC. Kingston B, et al. Among authors: hou y. Cancer Discov. 2024 Feb 8;14(2):274-289. doi: 10.1158/2159-8290.CD-22-1387. Cancer Discov. 2024. PMID: 37982575 Free PMC article.
Dual-mechanism estrogen receptor inhibitors.
Min J, Nwachukwu JC, Min CK, Njeri JW, Srinivasan S, Rangarajan ES, Nettles CC, Sanabria Guillen V, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH, Novick S, Pascal BD, Houtman R, Griffin PR, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. Min J, et al. Among authors: hou y. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):e2101657118. doi: 10.1073/pnas.2101657118. Proc Natl Acad Sci U S A. 2021. PMID: 34452998 Free PMC article.
Asymmetric allostery in estrogen receptor-α homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Min CK, Nwachukwu JC, Hou Y, Russo RJ, Papa A, Min J, Peng R, Kim SH, Ziegler Y, Rangarajan ES, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. Min CK, et al. Among authors: hou y. Proc Natl Acad Sci U S A. 2024 Jun 11;121(24):e2321344121. doi: 10.1073/pnas.2321344121. Epub 2024 Jun 3. Proc Natl Acad Sci U S A. 2024. PMID: 38830107
Asymmetric Allostery in Estrogen Receptor-α Homodimers Drives Responses to the Ensemble of Estrogens in the Hormonal Milieu.
Min CK, Nwachukwu JC, Hou Y, Russo RJ, Papa A, Min J, Peng R, Kim SH, Ziegler Y, Rangarajan ES, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. Min CK, et al. Among authors: hou y. bioRxiv [Preprint]. 2024 Apr 13:2024.04.10.588871. doi: 10.1101/2024.04.10.588871. bioRxiv. 2024. PMID: 38645081 Free PMC article. Preprint.
PPARα phosphorylation regulates colorectal tumor immune escape.
Gou Q, Tian X, Dong C, Yan B, Chen M, Shi J, Yang L, Hou Y. Gou Q, et al. Among authors: hou y. J Biol Chem. 2024 Jun 4:107447. doi: 10.1016/j.jbc.2024.107447. Online ahead of print. J Biol Chem. 2024. PMID: 38844134 Free article.
A single-cell transcriptome atlas of human euploid and aneuploid blastocysts.
Wang S, Leng L, Wang Q, Gu Y, Li J, An Y, Deng Q, Xie P, Cheng C, Chen X, Zhou Q, Lu J, Chen F, Liu L, Yang H, Wang J, Xu X, Hou Y, Gong F, Hu L, Lu G, Shang Z, Lin G. Wang S, et al. Among authors: hou y. Nat Genet. 2024 Jun 5. doi: 10.1038/s41588-024-01788-6. Online ahead of print. Nat Genet. 2024. PMID: 38839885
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