MacDonald PE - Search Results

1

Modulation of insulin secretion by RBFOX2-mediated alternative splicing.

Moss ND, Wells KL, Theis A, Kim YK, Spigelman AF, Liu X, MacDonald PE, Sussel L. Moss ND, et al. Among authors: macdonald pe. Nat Commun. 2023 Nov 25;14(1):7732. doi: 10.1038/s41467-023-43605-4. Nat Commun. 2023. PMID: 38007492 Free PMC article.

2

A pancreatic islet-specific microRNA regulates insulin secretion.

Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M. Poy MN, et al. Among authors: macdonald pe. Nature. 2004 Nov 11;432(7014):226-30. doi: 10.1038/nature03076. Nature. 2004. PMID: 15538371

3

Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells.

Pigeau GM, Kolic J, Ball BJ, Hoppa MB, Wang YW, Rückle T, Woo M, Manning Fox JE, MacDonald PE. Pigeau GM, et al. Among authors: macdonald pe. Diabetes. 2009 Sep;58(9):2084-92. doi: 10.2337/db08-1371. Epub 2009 Jun 23. Diabetes. 2009. PMID: 19549714 Free PMC article.

4

Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.

Hamming KS, Soliman D, Webster NJ, Searle GJ, Matemisz LC, Liknes DA, Dai XQ, Pulinilkunnil T, Riedel MJ, Dyck JR, Macdonald PE, Light PE. Hamming KS, et al. Among authors: macdonald pe. Diabetes. 2010 Jul;59(7):1686-93. doi: 10.2337/db09-0630. Epub 2010 Apr 22. Diabetes. 2010. PMID: 20413506 Free PMC article.

5

Voltage-dependent K(+) channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans.

Spigelman AF, Dai X, MacDonald PE. Spigelman AF, et al. Among authors: macdonald pe. Diabetologia. 2010 Sep;53(9):1917-26. doi: 10.1007/s00125-010-1759-z. Epub 2010 May 6. Diabetologia. 2010. PMID: 20446079

6

SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.

Dai XQ, Plummer G, Casimir M, Kang Y, Hajmrle C, Gaisano HY, Manning Fox JE, MacDonald PE. Dai XQ, et al. Among authors: macdonald pe. Diabetes. 2011 Mar;60(3):838-47. doi: 10.2337/db10-0440. Epub 2011 Jan 24. Diabetes. 2011. PMID: 21266332 Free PMC article.

7

The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.

Dai XQ, Manning Fox JE, Chikvashvili D, Casimir M, Plummer G, Hajmrle C, Spigelman AF, Kin T, Singer-Lahat D, Kang Y, Shapiro AM, Gaisano HY, Lotan I, Macdonald PE. Dai XQ, et al. Among authors: macdonald pe. Diabetologia. 2012 Jun;55(6):1709-20. doi: 10.1007/s00125-012-2512-6. Epub 2012 Mar 13. Diabetologia. 2012. PMID: 22411134

8

In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking.

Cai EP, Casimir M, Schroer SA, Luk CT, Shi SY, Choi D, Dai XQ, Hajmrle C, Spigelman AF, Zhu D, Gaisano HY, MacDonald PE, Woo M. Cai EP, et al. Among authors: macdonald pe. Diabetes. 2012 Jul;61(7):1708-18. doi: 10.2337/db11-1344. Epub 2012 Apr 12. Diabetes. 2012. PMID: 22498697 Free PMC article.

9

Functional plasticity of the human infant β-cell exocytotic phenotype.

Fox JE, Seeberger K, Dai XQ, Lyon J, Spigelman AF, Kolic J, Hajmrle C, Joseph JW, Kin T, Shapiro AM, Korbutt G, MacDonald PE. Fox JE, et al. Among authors: macdonald pe. Endocrinology. 2013 Apr;154(4):1392-9. doi: 10.1210/en.2012-1934. Epub 2013 Feb 28. Endocrinology. 2013. PMID: 23449893

10

Distinct and opposing roles for the phosphatidylinositol 3-OH kinase catalytic subunits p110α and p110β in the regulation of insulin secretion from rodent and human beta cells.

Kolic J, Spigelman AF, Plummer G, Leung E, Hajmrle C, Kin T, Shapiro AM, Manning Fox JE, MacDonald PE. Kolic J, et al. Among authors: macdonald pe. Diabetologia. 2013 Jun;56(6):1339-49. doi: 10.1007/s00125-013-2882-4. Epub 2013 Apr 9. Diabetologia. 2013. PMID: 23568272

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