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Page 1
Sickle cell allele HBB-rs334(T) is associated with decreased risk of childhood Burkitt lymphoma in East Africa.
Hong HG, Gouveia MH, Ogwang MD, Kerchan P, Reynolds SJ, Tenge CN, Were PA, Kuremu RT, Wekesa WN, Masalu N, Kawira E, Kinyera T, Wang X, Zhou J, Leal TP, Otim I, Legason ID, Nabalende H, Dhudha H, Mumia M, Baker FS, Okusolubo T, Ayers LW, Bhatia K, Goedert JJ, Woo J, Manning M, Cole N, Luo W, Hicks B, Chagaluka G, Johnston WT, Mutalima N, Borgstein E, Liomba GN, Kamiza S, Mkandawire N, Mitambo C, Molyneux EM, Newton R, Hutchinson A, Yeager M, Adeyemo AA, Thein SL, Rotimi CN, Chanock SJ, Prokunina-Olsson L, Mbulaiteye SM. Hong HG, et al. Among authors: leal tp. Am J Hematol. 2024 Jan;99(1):113-123. doi: 10.1002/ajh.27149. Epub 2023 Nov 27. Am J Hematol. 2024. PMID: 38009642
Genetic signatures of gene flow and malaria-driven natural selection in sub-Saharan populations of the "endemic Burkitt Lymphoma belt".
Gouveia MH, Bergen AW, Borda V, Nunes K, Leal TP, Ogwang MD, Yeboah ED, Mensah JE, Kinyera T, Otim I, Nabalende H, Legason ID, Mpoloka SW, Mokone GG, Kerchan P, Bhatia K, Reynolds SJ, Birtwum RB, Adjei AA, Tettey Y, Tay E, Hoover R, Pfeiffer RM, Biggar RJ, Goedert JJ, Prokunina-Olsson L, Dean M, Yeager M, Lima-Costa MF, Hsing AW, Tishkoff SA, Chanock SJ, Tarazona-Santos E, Mbulaiteye SM. Gouveia MH, et al. Among authors: leal tp. PLoS Genet. 2019 Mar 8;15(3):e1008027. doi: 10.1371/journal.pgen.1008027. eCollection 2019 Mar. PLoS Genet. 2019. PMID: 30849090 Free PMC article.
Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging.
Gouveia MH, Cesar CC, Santolalla ML, Anna HPS, Scliar MO, Leal TP, Araújo NM, Soares-Souza GB, Magalhães WCS, Mata IF, Ferri CP, Castro-Costa E, Mbulaiteye SM, Tishkoff SA, Shriner D, Rotimi CN, Tarazona-Santos E, Lima-Costa MF. Gouveia MH, et al. Among authors: leal tp. Sci Rep. 2019 Dec 2;9(1):18085. doi: 10.1038/s41598-019-53988-4. Sci Rep. 2019. PMID: 31792241 Free PMC article.
Origins, Admixture Dynamics, and Homogenization of the African Gene Pool in the Americas.
Gouveia MH, Borda V, Leal TP, Moreira RG, Bergen AW, Kehdy FSG, Alvim I, Aquino MM, Araujo GS, Araujo NM, Furlan V, Liboredo R, Machado M, Magalhaes WCS, Michelin LA, Rodrigues MR, Rodrigues-Soares F, Sant Anna HP, Santolalla ML, Scliar MO, Soares-Souza G, Zamudio R, Zolini C, Bortolini MC, Dean M, Gilman RH, Guio H, Rocha J, Pereira AC, Barreto ML, Horta BL, Lima-Costa MF, Mbulaiteye SM, Chanock SJ, Tishkoff SA, Yeager M, Tarazona-Santos E. Gouveia MH, et al. Among authors: leal tp. Mol Biol Evol. 2020 Jun 1;37(6):1647-1656. doi: 10.1093/molbev/msaa033. Mol Biol Evol. 2020. PMID: 32128591 Free PMC article.
Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes.
Scliar MO, Sant'Anna HP, Santolalla ML, Leal TP, Araújo NM, Alvim I, Borda V, Magalhães WCS, Gouveia MH, Lyra R, Machado M, Michelin L, Rodrigues MR, Araújo GS, Kehdy FSG, Zolini C, Peixoto SV, Luizon MR, Lobo F, Naslavsky MS, Yamamoto GL, Duarte YAO, Hansen MEB, Norris SA, Gilman RH, Guio H, Hsing AW, Mbulaiteye SM, Mensah J, Dutil J, Yeager M, Yeboah E, Tishkoff SA, Choudhury A, Ramsay M, Passos-Bueno MR, Zatz M, O Connor TD, Pereira AC, Barreto ML, Lima-Costa MF, Horta BL, Tarazona-Santos E. Scliar MO, et al. Among authors: leal tp. Int J Obes (Lond). 2021 May;45(5):1017-1029. doi: 10.1038/s41366-021-00761-1. Epub 2021 Feb 26. Int J Obes (Lond). 2021. PMID: 33633342 Free PMC article.
Socioeconomic Position, But Not African Genomic Ancestry, Is Associated With Blood Pressure in the Bambui-Epigen (Brazil) Cohort Study of Aging.
Lima-Costa MF, Mambrini JV, Leite ML, Peixoto SV, Firmo JO, Loyola Filho AI, Gouveia MH, Leal TP, Pereira AC, Macinko J, Tarazona-Santos E. Lima-Costa MF, et al. Among authors: leal tp. Hypertension. 2016 Feb;67(2):349-55. doi: 10.1161/HYPERTENSIONAHA.115.06609. Epub 2015 Dec 28. Hypertension. 2016. PMID: 26711733
NAToRA, a relatedness-pruning method to minimize the loss of dataset size in genetic and omics analyses.
Leal TP, Furlan VC, Gouveia MH, Saraiva Duarte JM, Fonseca PA, Tou R, Scliar MO, Araujo GS, Costa LF, Zolini C, Peixoto MGCD, Carvalho MRS, Lima-Costa MF, Gilman RH, Tarazona-Santos E, Rodrigues MR. Leal TP, et al. Comput Struct Biotechnol J. 2022 Apr 9;20:1821-1828. doi: 10.1016/j.csbj.2022.04.009. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35521552 Free PMC article.
Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations.
Kehdy FS, Gouveia MH, Machado M, Magalhães WC, Horimoto AR, Horta BL, Moreira RG, Leal TP, Scliar MO, Soares-Souza GB, Rodrigues-Soares F, Araújo GS, Zamudio R, Sant Anna HP, Santos HC, Duarte NE, Fiaccone RL, Figueiredo CA, Silva TM, Costa GN, Beleza S, Berg DE, Cabrera L, Debortoli G, Duarte D, Ghirotto S, Gilman RH, Gonçalves VF, Marrero AR, Muniz YC, Weissensteiner H, Yeager M, Rodrigues LC, Barreto ML, Lima-Costa MF, Pereira AC, Rodrigues MR, Tarazona-Santos E; Brazilian EPIGEN Project Consortium. Kehdy FS, et al. Among authors: leal tp. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8696-701. doi: 10.1073/pnas.1504447112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124090 Free PMC article.
Reducing cryptic relatedness in genomic data sets via a central node exclusion algorithm.
Fonseca PAS, Leal TP, Santos FC, Gouveia MH, Id-Lahoucine S, Rosse IC, Ventura RV, Bruneli FAT, Machado MA, Peixoto MGCD, Tarazona-Santos E, Carvalho MRS. Fonseca PAS, et al. Among authors: leal tp. Mol Ecol Resour. 2018 May;18(3):435-447. doi: 10.1111/1755-0998.12746. Epub 2018 Jan 25. Mol Ecol Resour. 2018. PMID: 29271609
29 results