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349 results

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Page 1
GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies.
Benbarche S, Pineda JMB, Galvis LB, Biswas J, Liu B, Wang E, Zhang Q, Hogg SJ, Lyttle K, Dahi A, Lewis AM, Sarchi M, Rahman J, Fox N, Ai Y, Mehta S, Garippa R, Ortiz-Pacheco J, Li Z, Monetti M, Stanley RF, Doulatov S, Bradley RK, Abdel-Wahab O. Benbarche S, et al. Among authors: abdel wahab o. Mol Cell. 2024 May 16;84(10):1886-1903.e10. doi: 10.1016/j.molcel.2024.04.006. Epub 2024 Apr 29. Mol Cell. 2024. PMID: 38688280 Free article.
A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies.
Liu X, Devadiga SA, Stanley RF, Morrow RM, Janssen KA, Quesnel-Vallières M, Pomp O, Moverley AA, Li C, Skuli N, Carroll MP, Huang J, Wallace DC, Lynch KW, Abdel-Wahab O, Klein PS. Liu X, et al. Among authors: abdel wahab o. J Clin Invest. 2024 May 7:e175619. doi: 10.1172/JCI175619. Online ahead of print. J Clin Invest. 2024. PMID: 38713535 Free article.
SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer.
Ma HL, Bizet M, Soares Da Costa C, Murisier F, de Bony EJ, Wang MK, Yoshimi A, Lin KT, Riching KM, Wang X, Beckman JI, Arya S, Droin N, Calonne E, Hassabi B, Zhang QY, Li A, Putmans P, Malbec L, Hubert C, Lan J, Mies F, Yang Y, Solary E, Daniels DL, Gupta YK, Deplus R, Abdel-Wahab O, Yang YG, Fuks F. Ma HL, et al. Mol Cell. 2023 Dec 7;83(23):4239-4254.e10. doi: 10.1016/j.molcel.2023.11.003. Mol Cell. 2023. PMID: 38065062
Targeting the cBAF complex in T-ALL.
Chen B, Abdel-Wahab O. Chen B, et al. Among authors: abdel wahab o. Blood. 2024 Feb 15;143(7):566-567. doi: 10.1182/blood.2023023040. Blood. 2024. PMID: 38358848 No abstract available.
A new SAGA for AML: targeting SGF29 in AML.
Biswas J, Abdel-Wahab O. Biswas J, et al. Among authors: abdel wahab o. Blood. 2024 Feb 22;143(8):657-658. doi: 10.1182/blood.2023023442. Blood. 2024. PMID: 38386429 No abstract available.
Vemurafenib and Obinutuzumab as Frontline Therapy for Hairy Cell Leukemia.
Park JH, Devlin S, Durham BH, Winer ES, Huntington S, von Keudell G, Vemuri S, Shukla M, Falco V, Cuello B, Gore S, Stone R, Abdel-Wahab O, Tallman MS. Park JH, et al. NEJM Evid. 2023 Oct;2(10):EVIDoa2300074. doi: 10.1056/EVIDoa2300074. Epub 2023 Sep 21. NEJM Evid. 2023. PMID: 38320179 Free PMC article.
Mixed histiocytic neoplasms: A multicentre series revealing diverse somatic mutations and responses to targeted therapy.
Friedman JS, Durham BH, Reiner AS, Yabe M, Petrova-Drus K, Dogan A, Pulitzer M, Busam KJ, Francis JH, Rampal RK, Ulaner GA, Reddy R, Yeh R, Hatzoglou V, Lacouture ME, Rotemberg V, Mazor RD, Hershkovitz-Rokah O, Shpilberg O, Goyal G, Go RS, Abeykoon JP, Rech K, Morlote D, Fidai S, Gannamani V, Zia M, Abdel-Wahab O, Panageas KS, Rosenblum MK, Diamond EL. Friedman JS, et al. Among authors: abdel wahab o. Br J Haematol. 2024 Apr 12. doi: 10.1111/bjh.19462. Online ahead of print. Br J Haematol. 2024. PMID: 38613141
349 results