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Neurons undergo pathogenic metabolic reprogramming in models of familial ALS.
Riechers SP, Mojsilovic-Petrovic J, Belton TB, Chakrabarty RP, Garjani M, Medvedeva V, Dalton C, Wong YC, Chandel NS, Dienel G, Kalb RG. Riechers SP, et al. Among authors: chandel ns. Mol Metab. 2022 Jun;60:101468. doi: 10.1016/j.molmet.2022.101468. Epub 2022 Mar 3. Mol Metab. 2022. PMID: 35248787 Free PMC article.
Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice.
McElroy GS, Chakrabarty RP, D'Alessandro KB, Hu YS, Vasan K, Tan J, Stoolman JS, Weinberg SE, Steinert EM, Reyfman PA, Singer BD, Ladiges WC, Gao L, Lopéz-Barneo J, Ridge K, Budinger GRS, Chandel NS. McElroy GS, et al. Among authors: chandel ns. Sci Rep. 2022 Mar 25;12(1):5196. doi: 10.1038/s41598-022-09074-3. Sci Rep. 2022. PMID: 35338200 Free PMC article.
Author Correction: Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice.
McElroy GS, Chakrabarty RP, D'Alessandro KB, Hu YS, Vasan K, Tan J, Stoolman JS, Weinberg SE, Steinert EM, Reyfman PA, Singer BD, Ladiges WC, Gao L, Lopéz-Barneo J, Ridge K, Budinger GRS, Chandel NS. McElroy GS, et al. Among authors: chandel ns. Sci Rep. 2022 May 17;12(1):8191. doi: 10.1038/s41598-022-12069-9. Sci Rep. 2022. PMID: 35581238 Free PMC article. No abstract available.
Human iPSC-derived cerebral organoids model features of Leigh syndrome and reveal abnormal corticogenesis.
Romero-Morales AI, Robertson GL, Rastogi A, Rasmussen ML, Temuri H, McElroy GS, Chakrabarty RP, Hsu L, Almonacid PM, Millis BA, Chandel NS, Cartailler JP, Gama V. Romero-Morales AI, et al. Among authors: chandel ns. Development. 2022 Oct 15;149(20):dev199914. doi: 10.1242/dev.199914. Epub 2022 Jul 6. Development. 2022. PMID: 35792828 Free PMC article.
Beyond ATP, new roles of mitochondria.
Chakrabarty RP, Chandel NS. Chakrabarty RP, et al. Among authors: chandel ns. Biochem (Lond). 2022 Aug;44(4):2-8. doi: 10.1042/bio_2022_119. Epub 2022 Aug 23. Biochem (Lond). 2022. PMID: 36248614 Free PMC article.
297 results