Dey K - Search Results

1

Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.

Kang JB, Shen AZ, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta KA, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, Ananthakrishnan AN, Jagadeesh K, Dey K; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Daly MJ, Xavier RJ, Donlin LT, Anolik JH, Powell JE, Rao DA, Brenner MB, Gutierrez-Arcelus M, Luo Y, Sakaue S, Raychaudhuri S. Kang JB, et al. Among authors: dey k. Nat Genet. 2023 Dec;55(12):2255-2268. doi: 10.1038/s41588-023-01586-6. Epub 2023 Nov 30. Nat Genet. 2023. PMID: 38036787 Free PMC article.

2

Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements.

Amariuta T, Ishigaki K, Sugishita H, Ohta T, Koido M, Dey KK, Matsuda K, Murakami Y, Price AL, Kawakami E, Terao C, Raychaudhuri S. Amariuta T, et al. Among authors: dey kk. Nat Genet. 2020 Dec;52(12):1346-1354. doi: 10.1038/s41588-020-00740-8. Epub 2020 Nov 30. Nat Genet. 2020. PMID: 33257898 Free PMC article.

3

Genome-wide enhancer maps link risk variants to disease genes.

Nasser J, Bergman DT, Fulco CP, Guckelberger P, Doughty BR, Patwardhan TA, Jones TR, Nguyen TH, Ulirsch JC, Lekschas F, Mualim K, Natri HM, Weeks EM, Munson G, Kane M, Kang HY, Cui A, Ray JP, Eisenhaure TM, Collins RL, Dey K, Pfister H, Price AL, Epstein CB, Kundaje A, Xavier RJ, Daly MJ, Huang H, Finucane HK, Hacohen N, Lander ES, Engreitz JM. Nasser J, et al. Among authors: dey k. Nature. 2021 May;593(7858):238-243. doi: 10.1038/s41586-021-03446-x. Epub 2021 Apr 7. Nature. 2021. PMID: 33828297 Free PMC article.

4

Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics.

Jagadeesh KA, Dey KK, Montoro DT, Mohan R, Gazal S, Engreitz JM, Xavier RJ, Price AL, Regev A. Jagadeesh KA, et al. Among authors: dey kk. bioRxiv [Preprint]. 2021 Nov 23:2021.03.19.436212. doi: 10.1101/2021.03.19.436212. bioRxiv. 2021. PMID: 34845454 Free PMC article. Updated. Preprint.

5

Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity.

Gazal S, Weissbrod O, Hormozdiari F, Dey KK, Nasser J, Jagadeesh KA, Weiner DJ, Shi H, Fulco CP, O'Connor LJ, Pasaniuc B, Engreitz JM, Price AL. Gazal S, et al. Among authors: dey kk. Nat Genet. 2022 Jun;54(6):827-836. doi: 10.1038/s41588-022-01087-y. Epub 2022 Jun 6. Nat Genet. 2022. PMID: 35668300 Free PMC article.

6

Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data.

Zhang MJ, Hou K, Dey KK, Sakaue S, Jagadeesh KA, Weinand K, Taychameekiatchai A, Rao P, Pisco AO, Zou J, Wang B, Gandal M, Raychaudhuri S, Pasaniuc B, Price AL. Zhang MJ, et al. Among authors: dey kk. Nat Genet. 2022 Oct;54(10):1572-1580. doi: 10.1038/s41588-022-01167-z. Epub 2022 Sep 1. Nat Genet. 2022. PMID: 36050550 Free PMC article.

7

SAIGE-GENE+ improves the efficiency and accuracy of set-based rare variant association tests.

Zhou W, Bi W, Zhao Z, Dey KK, Jagadeesh KA, Karczewski KJ, Daly MJ, Neale BM, Lee S. Zhou W, et al. Among authors: dey kk. Nat Genet. 2022 Oct;54(10):1466-1469. doi: 10.1038/s41588-022-01178-w. Epub 2022 Sep 22. Nat Genet. 2022. PMID: 36138231 Free PMC article.

8

Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics.

Jagadeesh KA, Dey KK, Montoro DT, Mohan R, Gazal S, Engreitz JM, Xavier RJ, Price AL, Regev A. Jagadeesh KA, et al. Among authors: dey kk. Nat Genet. 2022 Oct;54(10):1479-1492. doi: 10.1038/s41588-022-01187-9. Epub 2022 Sep 29. Nat Genet. 2022. PMID: 36175791 Free PMC article.

9

Publisher Correction: SAIGE-GENE+ improves the efficiency and accuracy of set-based rare variant association tests.

Zhou W, Bi W, Zhao Z, Dey KK, Jagadeesh KA, Karczewski KJ, Daly MJ, Neale BM, Lee S. Zhou W, et al. Among authors: dey kk. Nat Genet. 2022 Nov;54(11):1755. doi: 10.1038/s41588-022-01220-x. Nat Genet. 2022. PMID: 36257984 Free PMC article. No abstract available.

10

Polygenic architecture of rare coding variation across 394,783 exomes.

Weiner DJ, Nadig A, Jagadeesh KA, Dey KK, Neale BM, Robinson EB, Karczewski KJ, O'Connor LJ. Weiner DJ, et al. Among authors: dey kk. Nature. 2023 Feb;614(7948):492-499. doi: 10.1038/s41586-022-05684-z. Epub 2023 Feb 8. Nature. 2023. PMID: 36755099 Free PMC article.

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