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Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity.
Awad D, Cao PHA, Pulliam TL, Spradlin M, Subramani E, Tellman TV, Ribeiro CF, Muzzioli R, Jewell BE, Pakula H, Ackroyd JJ, Murray MM, Han JJ, Leng M, Jain A, Piyarathna B, Liu J, Song X, Zhang J, Klekers AR, Drake JM, Ittmann MM, Coarfa C, Piwnica-Worms D, Farach-Carson MC, Loda M, Eberlin LS, Frigo DE. Awad D, et al. Among authors: frigo de. Cancer Res. 2024 Mar 4;84(5):703-724. doi: 10.1158/0008-5472.CAN-23-0555. Cancer Res. 2024. PMID: 38038968
Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer.
Kaushik AK, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, Zaslavsky A, Putluri V, Vasu VT, Zhang Y, Khan AS, Lloyd S, Szafran AT, Dasgupta S, Bader DA, Stossi F, Li H, Samanta S, Cao X, Tsouko E, Huang S, Frigo DE, Chan L, Edwards DP, Kaipparettu BA, Mitsiades N, Weigel NL, Mancini M, McGuire SE, Mehra R, Ittmann MM, Chinnaiyan AM, Putluri N, Palapattu GS, Michailidis G, Sreekumar A. Kaushik AK, et al. Among authors: frigo de. Nat Commun. 2016 May 19;7:11612. doi: 10.1038/ncomms11612. Nat Commun. 2016. PMID: 27194471 Free PMC article.
Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression.
Blessing AM, Rajapakshe K, Reddy Bollu L, Shi Y, White MA, Pham AH, Lin C, Jonsson P, Cortes CJ, Cheung E, La Spada AR, Bast RC Jr, Merchant FA, Coarfa C, Frigo DE. Blessing AM, et al. Among authors: frigo de. Autophagy. 2017 Mar 4;13(3):506-521. doi: 10.1080/15548627.2016.1268300. Epub 2016 Dec 15. Autophagy. 2017. PMID: 27977328 Free PMC article.
GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling.
White MA, Tsouko E, Lin C, Rajapakshe K, Spencer JM, Wilkenfeld SR, Vakili SS, Pulliam TL, Awad D, Nikolos F, Katreddy RR, Kaipparettu BA, Sreekumar A, Zhang X, Cheung E, Coarfa C, Frigo DE. White MA, et al. Among authors: frigo de. Endocr Relat Cancer. 2018 Apr;25(4):453-469. doi: 10.1530/ERC-17-0051. Epub 2018 Feb 5. Endocr Relat Cancer. 2018. PMID: 29431615 Free PMC article.
59 results