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CC16 drives VLA-2-dependent SPLUNC1 expression.
Iannuzo N, Welfley H, Li NC, Johnson MDL, Rojas-Quintero J, Polverino F, Guerra S, Li X, Cusanovich DA, Langlais PR, Ledford JG. Iannuzo N, et al. Among authors: li x, li nc. Front Immunol. 2023 Nov 20;14:1277582. doi: 10.3389/fimmu.2023.1277582. eCollection 2023. Front Immunol. 2023. PMID: 38053993 Free PMC article.
Myeloid-associated differentiation marker is a novel SP-A-associated transmembrane protein whose expression on airway epithelial cells correlates with asthma severity.
Dy ABC, Langlais PR, Barker NK, Addison KJ, Tanyaratsrisakul S, Boitano S, Christenson SA, Kraft M, Meyers D, Bleecker ER, Li X, Ledford JG. Dy ABC, et al. Among authors: li x. Sci Rep. 2021 Dec 3;11(1):23392. doi: 10.1038/s41598-021-02869-w. Sci Rep. 2021. PMID: 34862427 Free PMC article.
Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.
Li X, Guerra S, Ledford JG, Kraft M, Li H, Hastie AT, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Meyers DA, Bleecker ER. Li X, et al. Among authors: li h. Am J Respir Crit Care Med. 2023 Feb 15;207(4):438-451. doi: 10.1164/rccm.202206-1230OC. Am J Respir Crit Care Med. 2023. PMID: 36066606 Free PMC article.
The effect of BPIFA1/SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelium.
Schaefer N, Li X, Seibold MA, Jarjour NN, Denlinger LC, Castro M, Coverstone AM, Teague WG, Boomer J, Bleecker ER, Meyers DA, Moore WC, Hawkins GA, Fahy J, Phillips BR, Mauger DT, Dakhama A, Gellatly S, Pavelka N, Berman R, Di YP, Wenzel SE, Chu HW. Schaefer N, et al. Among authors: li x. JCI Insight. 2019 Apr 18;4(8):e127237. doi: 10.1172/jci.insight.127237. eCollection 2019 Apr 18. JCI Insight. 2019. PMID: 30996135 Free PMC article.
Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways.
Li X, Christenson SA, Modena B, Li H, Busse WW, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Moore WC, Woodruff PG, Kaminski N, Wenzel SE, Bleecker ER, Meyers DA; NHLBI Severe Asthma Research Program (SARP). Li X, et al. Among authors: li h. J Allergy Clin Immunol. 2021 Mar;147(3):894-909. doi: 10.1016/j.jaci.2020.07.030. Epub 2020 Aug 11. J Allergy Clin Immunol. 2021. PMID: 32795586 Free PMC article.
The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma.
Hawkins GA, Robinson MB, Hastie AT, Li X, Li H, Moore WC, Howard TD, Busse WW, Erzurum SC, Wenzel SE, Peters SP, Meyers DA, Bleecker ER; National Heart, Lung, and Blood Institute–sponsored Severe Asthma Research Program (SARP). Hawkins GA, et al. Among authors: li x, li h. J Allergy Clin Immunol. 2012 Aug;130(2):510-5.e1. doi: 10.1016/j.jaci.2012.03.018. Epub 2012 May 1. J Allergy Clin Immunol. 2012. PMID: 22554704 Free PMC article.
Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma.
Li X, Hastie AT, Peters MC, Hawkins GA, Phipatanakul W, Li H, Moore WC, Busse WW, Castro M, Erzurum SC, Gaston B, Israel E, Jarjour NN, Levy BD, Wenzel SE, Meyers DA, Fahy JV, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program (SARP) Networks. Li X, et al. Among authors: li h. J Allergy Clin Immunol. 2020 Jan;145(1):430-433. doi: 10.1016/j.jaci.2019.08.031. Epub 2019 Sep 9. J Allergy Clin Immunol. 2020. PMID: 31513878 Free PMC article.
Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.
Kasela S, Ortega VE, Martorella M, Garudadri S, Nguyen J, Ampleford E, Pasanen A, Nerella S, Buschur KL, Barjaktarevic IZ, Barr RG, Bleecker ER, Bowler RP, Comellas AP, Cooper CB, Couper DJ, Criner GJ, Curtis JL, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Krishnan JA, Martinez FJ, McDonald MN, Meyers DA, Paine R 3rd, Peters SP, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Levy BD, Li X, Moore WC, Wenzel SE, Zein J; NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS); NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Langelier C, Woodruff PG, Lappalainen T, Christenson SA. Kasela S, et al. Among authors: li x. Genome Med. 2021 Apr 21;13(1):66. doi: 10.1186/s13073-021-00866-2. Genome Med. 2021. PMID: 33883027 Free PMC article.
Multiethnic genome-wide and HLA association study of total serum IgE level.
Daya M, Cox C, Acevedo N, Boorgula MP, Campbell M, Chavan S, Cho MH, David GL, Kachroo P, Lasky-Su J, Li X, McHugh CP, Qiao D, Rafaels N, Beck LA, Bleecker ER, Caraballo L, Cupples AL, Figueiredo CA, Gallo RL, Hanifin J, Hansel NN, Hata TR, Hersh CP, Knight-Madden J, Leung DYM, Guttman-Yassky E, Meyers DA, O'Connor G, Ober C, Ong PY, Ortega VE, Paller AS, Putcha N, Reed RM, Schneider LC, Silverman EK, Slifka MK, Spergel JM, Vasan RS, Viaud-Martinez KA, Watson H, Weiss ST; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Ruczinski I, Beaty TH, Mathias RA, Barnes KC. Daya M, et al. Among authors: li x. J Allergy Clin Immunol. 2021 Dec;148(6):1589-1595. doi: 10.1016/j.jaci.2021.09.011. Epub 2021 Sep 15. J Allergy Clin Immunol. 2021. PMID: 34536413 Free PMC article.
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